ENSDARG00000003570


Danio rerio

Features
Gene ID: ENSDARG00000003570
  
Biological name :hsp90b1
  
Synonyms : heat shock protein 90, beta (grp94), member 1 / hsp90b1
  
Possible biological names infered from orthology : heat shock protein 90 beta family member 1 / P08113 / P14625
  
Species: Danio rerio
  
Chr. number: 4
Strand: 1
Band:
Gene start: 9836465
Gene end: 9843836
  
Corresponding Affymetrix probe sets: Dr.25548.1.S1_at (Zebrafish Array)   NM_198210_at (Zebrafish Genome Array with custom cdf files)   
  
Cross references: Ensembl peptide - ENSDARP00000013441
NCBI entrez gene - 386590     See in Manteia.
RefSeq - NM_198210
RefSeq Peptide - NP_937853
swissprot - Q7T3L3
ZFIN ID - ZDB-GENE-031002-1
Ensembl - ENSDARG00000003570
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 HSP90B1ENSGALG00000033789Gallus gallus
 P14625ENSG00000166598Homo sapiens
 P08113ENSMUSG00000020048Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Q90474 / hsp90aa1.1 / heat shock protein 90, alpha (cytosolic), class A member 1, tandem duplicate 1 / P07900* / P07901* / HSP90AA1* / Heat shock protein HSP 90-alpha * / heat shock protein...ENSDARG0000001047841
trap1 / TNF receptor-associated protein 1 / Q12931*ENSDARG0000002431725


Protein motifs (from Interpro)
Interpro ID Name
 IPR001404  Heat shock protein Hsp90 family
 IPR003594  Histidine kinase/HSP90-like ATPase
 IPR020568  Ribosomal protein S5 domain 2-type fold
 IPR020575  Heat shock protein Hsp90, N-terminal


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001666 response to hypoxia IDA
 biological_processGO:0006457 protein folding IEA
 biological_processGO:0006950 response to stress IEA
 biological_processGO:0035889 otolith tethering IMP
 biological_processGO:0050830 defense response to Gram-positive bacterium IMP
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0051082 unfolded protein binding IEA


Pathways (from Reactome)
Pathway description
Trafficking and processing of endosomal TLR
Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)
Interleukin-4 and Interleukin-13 signaling
Post-translational protein phosphorylation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0001094 whole organism whole organism viability , abnormal
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 ZFA:0005145 muscle muscle damaged , abnormal
Show

 ZFA:0009114 muscle cell muscle cell cytoskeleton disorganized , abnormal
Show

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSDARG00000003570 hsp90b1 / heat shock protein 90, beta (grp94), member 1 / P08113* / P14625* / heat shock protein 90 beta family member 1*  / complex






 

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