ENSDARG00000005002


Danio rerio

Features
Gene ID: ENSDARG00000005002
  
Biological name :brf1b
  
Synonyms : brf1b / BRF1, RNA polymerase III transcription initiation factor b
  
Possible biological names infered from orthology : BRF1 / BRF1, RNA polymerase III transcription initiation factor 90 kDa subunit / BRF1, RNA polymerase III transcription initiation factor subunit / Q92994
  
Species: Danio rerio
  
Chr. number: 20
Strand: 1
Band:
Gene start: 20901791
Gene end: 21018334
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSDARP00000038308
Ensembl peptide - ENSDARP00000149573
NCBI entrez gene - 334316     See in Manteia.
RefSeq - NM_199889
RefSeq Peptide - NP_956183
swissprot - Q5TZ89
ZFIN ID - ZDB-GENE-030131-6248
Ensembl - ENSDARG00000005002
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 BRF1ENSGALG00000011705Gallus gallus
 BRF1ENSG00000185024Homo sapiens
 Brf1ENSMUSG00000011158Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
brf1a / BRF1, RNA polymerase III transcription initiation factor a / BRF1* / Q92994* / BRF1, RNA polymerase III transcription initiation factor subunit* / BRF1, RNA polymerase III transcrip...ENSDARG0000001783561


Protein motifs (from Interpro)
Interpro ID Name
 IPR000812  Transcription factor TFIIB
 IPR011665  Brf1, TBP-binding domain
 IPR013137  Zinc finger, TFIIB-type
 IPR013150  Transcription factor TFIIB, cyclin-like domain
 IPR013763  Cyclin-like
 IPR029529  Transcription factor IIIB subunit Brf1


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0002574 thrombocyte differentiation IMP
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0006359 regulation of transcription by RNA polymerase III IEA
 biological_processGO:0006383 transcription by RNA polymerase III IEA
 biological_processGO:0021549 cerebellum development IMP
 biological_processGO:0070897 DNA-templated transcriptional preinitiation complex assembly IEA
 cellular_componentGO:0000126 transcription factor TFIIIB complex IEA
 molecular_functionGO:0001026 obsolete TFIIIB-type transcription factor activity IEA
 molecular_functionGO:0017025 TBP-class protein binding IEA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
RNA Polymerase III Transcription Initiation From Type 1 Promoter
RNA Polymerase III Transcription Initiation From Type 2 Promoter


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000100 cerebellum cerebellum disorganized , abnormal
cerebellum hypoplastic , abnormal
cerebellum axon morphology , abnormal
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 ZFA:0000107 eye eye decreased distance eye , abnormal
Show

 ZFA:0000445 optic tectum optic tectum decreased size , abnormal
Show

 ZFA:0001114 head head decreased size , abnormal
Show

 ZFA:0009323 thrombocyte thrombocyte decreased amount , abnormal
Show

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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