ENSDARG00000017835


Danio rerio

Features
Gene ID: ENSDARG00000017835
  
Biological name :brf1a
  
Synonyms : brf1a / BRF1, RNA polymerase III transcription initiation factor a
  
Possible biological names infered from orthology : BRF1 / BRF1, RNA polymerase III transcription initiation factor 90 kDa subunit / BRF1, RNA polymerase III transcription initiation factor subunit / Q92994
  
Species: Danio rerio
  
Chr. number: 13
Strand: 1
Band:
Gene start: 33368140
Gene end: 33449639
  
Corresponding Affymetrix probe sets: Dr.20342.1.S1_at (Zebrafish Array)   
  
Cross references: Ensembl peptide - ENSDARP00000114528
Ensembl peptide - ENSDARP00000029653
Ensembl peptide - ENSDARP00000132978
NCBI entrez gene - 334402     See in Manteia.
swissprot - B8A4L9
swissprot - F1R9S3
ZFIN ID - ZDB-GENE-030131-6334
Ensembl - ENSDARG00000017835
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 BRF1ENSGALG00000011705Gallus gallus
 BRF1ENSG00000185024Homo sapiens
 Brf1ENSMUSG00000011158Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
brf1b / BRF1, RNA polymerase III transcription initiation factor b / BRF1* / Q92994* / BRF1, RNA polymerase III transcription initiation factor subunit* / BRF1, RNA polymerase III transcrip...ENSDARG0000000500264


Protein motifs (from Interpro)
Interpro ID Name
 IPR000812  Transcription factor TFIIB
 IPR011665  Brf1, TBP-binding domain
 IPR013137  Zinc finger, TFIIB-type
 IPR013150  Transcription factor TFIIB, cyclin-like domain
 IPR013763  Cyclin-like
 IPR029529  Transcription factor IIIB subunit Brf1


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0006359 regulation of transcription by RNA polymerase III IEA
 biological_processGO:0006383 transcription by RNA polymerase III IEA
 biological_processGO:0030099 myeloid cell differentiation IMP
 biological_processGO:0030223 neutrophil differentiation IMP
 biological_processGO:0070897 DNA-templated transcriptional preinitiation complex assembly IEA
 cellular_componentGO:0000126 transcription factor TFIIIB complex IEA
 molecular_functionGO:0001026 obsolete TFIIIB-type transcription factor activity IEA
 molecular_functionGO:0017025 TBP-class protein binding IEA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
RNA Polymerase III Transcription Initiation From Type 1 Promoter
RNA Polymerase III Transcription Initiation From Type 2 Promoter


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000094 blood island blood island has fewer parts of type neutrophil , abnormal
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 ZFA:0009323 thrombocyte thrombocyte decreased amount , abnormal
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Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSDARG00000014994 tbp / Q7SXL3 / TATA box binding protein / P20226* / P29037*  / complex
 ENSDARG00000030267 gtf3aa / general transcription factor IIIAa / GTF3A* / Q92664* / transcription factor IIIA * / general transcription factor IIIA*  / complex / reaction
 ENSDARG00000071583 gtf3ab / general transcription factor IIIA, b / GTF3A* / Q92664* / transcription factor IIIA * / general transcription factor IIIA*  / complex / reaction






 

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