ENSDARG00000014994


Danio rerio

Features
Gene ID: ENSDARG00000014994
  
Biological name :tbp
  
Synonyms : Q7SXL3 / TATA box binding protein / tbp
  
Possible biological names infered from orthology : P20226 / P29037
  
Species: Danio rerio
  
Chr. number: 13
Strand: -1
Band:
Gene start: 24381344
Gene end: 24396199
  
Corresponding Affymetrix probe sets: Dr.2761.1.A1_at (Zebrafish Array)   NM_200096_at (Zebrafish Genome Array with custom cdf files)   
  
Cross references: Ensembl peptide - ENSDARP00000010211
Ensembl peptide - ENSDARP00000154436
NCBI entrez gene - 368882     See in Manteia.
RefSeq - NM_200096
RefSeq Peptide - NP_956390
swissprot - Q7SXL3
ZFIN ID - ZDB-GENE-030616-563
Ensembl - ENSDARG00000014994
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 TBPENSGALG00000011171Gallus gallus
 TBPENSG00000112592Homo sapiens
 TbpENSMUSG00000014767Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
tbpl2 / Q1JPY4 / TATA box binding protein like 2 / Q6SJ96* / Q6SJ95* / TATA box-binding protein-like protein 2 *ENSDARG0000009730265
tbpl1 / Q5U385 / TBP-like 1 / P62380* / P62340* / TATA-box binding protein like 1* / TATA box-binding protein-like protein 1 *ENSDARG0000003686824


Protein motifs (from Interpro)
Interpro ID Name
 IPR000814  TATA-box binding protein
 IPR030491  TATA-box binding protein, conserved site
 IPR033710  TATA-box binding protein, eukaryotic


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006352 DNA-templated transcription, initiation ISS
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0006359 regulation of transcription by RNA polymerase III IEA
 biological_processGO:0006366 transcription by RNA polymerase II ISS
 biological_processGO:0006383 transcription by RNA polymerase III ISS
 biological_processGO:0006402 mRNA catabolic process IMP
 biological_processGO:0007275 multicellular organism development IEA
 biological_processGO:0007369 gastrulation IMP
 cellular_componentGO:0005634 nucleus ISS
 cellular_componentGO:0005669 transcription factor TFIID complex ISS
 molecular_functionGO:0003677 DNA binding ISS


Pathways (from Reactome)
Pathway description
B-WICH complex positively regulates rRNA expression
RNA Polymerase II Pre-transcription Events
Regulation of TP53 Activity through Phosphorylation
RNA polymerase II transcribes snRNA genes
RNA Polymerase I Transcription Initiation
RNA Polymerase I Promoter Escape
RNA Polymerase II Promoter Escape
RNA Polymerase I Chain Elongation
RNA Polymerase II Transcription Pre-Initiation And Promoter Opening
RNA Polymerase I Transcription Termination
RNA Polymerase II Transcription Initiation
RNA Polymerase II Transcription Initiation And Promoter Clearance
RNA Polymerase III Transcription Initiation From Type 1 Promoter
RNA Polymerase III Transcription Initiation From Type 2 Promoter
RNA Polymerase III Transcription Initiation From Type 3 Promoter
Estrogen-dependent gene expression


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000092 axis axis decreased length , abnormal
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Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSDARG00000018698 carm1 / Q6DC04 / coactivator-associated arginine methyltransferase 1 / Q9WVG6* / Q86X55* / Histone-arginine methyltransferase CARM1 *  / complex / reaction
 ENSDARG00000041581 Q1LYE3 / znf143b / zinc finger protein 143b / P52747* / Zfp143* / ZNF143* / O70230* / zinc finger protein 143*  / complex / reaction
 ENSDARG00000010246 prmt1 / protein arginine methyltransferase 1 / Q99873* / Q9JIF0* / protein arginine N-methyltransferase 1*  / complex / reaction
 ENSDARG00000002060 brf2 / BRF2, RNA polymerase III transcription initiation factor / Q9HAW0* / BRF2, RNA polymerase III transcription initiation factor subunit*  / complex
 ENSDARG00000004111 esr1 / estrogen receptor 1 / P03372* / P19785* / Estrogen receptor *  / complex / reaction
 ENSDARG00000016526 gata3 / Q91428 / GATA binding protein 3 / P23771* / P23772* / Mus musculus GATA binding protein 3 (Gata3), transcript variant 3, mRNA.*  / complex / reaction
 ENSDARG00000017835 brf1a / BRF1, RNA polymerase III transcription initiation factor a / BRF1* / Q92994* / BRF1, RNA polymerase III transcription initiation factor subunit* / BRF1, RNA polymerase III transcrip...  / complex
 ENSDARG00000018257 ncoa1 / nuclear receptor coactivator 1 / P70365* / Q15788*  / complex / reaction
 ENSDARG00000030267 gtf3aa / general transcription factor IIIAa / GTF3A* / Q92664* / transcription factor IIIA * / general transcription factor IIIA*  / complex / reaction
 ENSDARG00000053685 gtf2a2 / general transcription factor IIA, 2 / P52657* / Q80ZM7* / general transcription factor IIA subunit 2* / Transcription initiation factor IIA subunit 2 *  / complex / reaction
 ENSDARG00000071583 gtf3ab / general transcription factor IIIA, b / GTF3A* / Q92664* / transcription factor IIIA * / general transcription factor IIIA*  / complex / reaction
 ENSDARG00000077404 ncoa3 / nuclear receptor coactivator 3 / Q9Y6Q9*  / complex / reaction






 

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