ENSDARG00000006818


Danio rerio

Features
Gene ID: ENSDARG00000006818
  
Biological name :urod
  
Synonyms : Q9PTS2 / urod / uroporphyrinogen decarboxylase
  
Possible biological names infered from orthology : P06132 / P70697
  
Species: Danio rerio
  
Chr. number: 2
Strand: -1
Band:
Gene start: 27556168
Gene end: 27575803
  
Corresponding Affymetrix probe sets: Dr.2166.1.S1_at (Zebrafish Array)   
  
Cross references: Ensembl peptide - ENSDARP00000023867
NCBI entrez gene - 30617     See in Manteia.
swissprot - Q9PTS2
ZFIN ID - ZDB-GENE-000208-18
Ensembl - ENSDARG00000006818
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ENSGALG00000010219Gallus gallus
 URODENSG00000126088Homo sapiens
 UrodENSMUSG00000028684Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR000257  Uroporphyrinogen decarboxylase (URO-D)
 IPR006361  Uroporphyrinogen decarboxylase HemE


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006778 porphyrin-containing compound metabolic process IDA
 biological_processGO:0006779 porphyrin-containing compound biosynthetic process IEA
 biological_processGO:0006782 protoporphyrinogen IX biosynthetic process IEA
 biological_processGO:0006783 heme biosynthetic process IBA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005829 cytosol IBA
 molecular_functionGO:0004853 uroporphyrinogen decarboxylase activity IDA
 molecular_functionGO:0016829 lyase activity IEA
 molecular_functionGO:0016831 carboxy-lyase activity IEA


Pathways (from Reactome)
Pathway description
Heme biosynthesis


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000007 blood blood quality , abnormal
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 ZFA:0000054 pericardium pericardium edematous , abnormal
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 ZFA:0000108 fin fin necrotic , abnormal
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 ZFA:0000114 heart heart quality , abnormal
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 ZFA:0001094 whole organism whole organism lethal (sensu genetics) , abnormal
whole organism viability , abnormal
whole organism photosensitive , abnormal
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 ZFA:0001439 anatomical system anatomical system quality , abnormal
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 ZFA:0009256 nucleate erythrocyte nucleate erythrocyte fluorescence , abnormal
nucleate erythrocyte autofluorescence , abnormal
nucleate erythrocyte increased fluorescence , abnormal
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Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSDARG00000006818 urod / Q9PTS2 / uroporphyrinogen decarboxylase / P06132* / P70697*  / complex






 

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