ENSDARG00000007370


Danio rerio

Features
Gene ID: ENSDARG00000007370
  
Biological name :dysf
  
Synonyms : dysf / dysferlin, limb girdle muscular dystrophy 2B (autosomal recessive)
  
Possible biological names infered from orthology : dysferlin / O75923 / Q9ESD7
  
Species: Danio rerio
  
Chr. number: 7
Strand: -1
Band:
Gene start: 25558275
Gene end: 25697285
  
Corresponding Affymetrix probe sets: Dr.11738.1.A1_at (Zebrafish Array)   
  
Cross references: Ensembl peptide - ENSDARP00000114340
Ensembl peptide - ENSDARP00000077055
NCBI entrez gene - 560924     See in Manteia.
RefSeq - XM_005172293
RefSeq - XM_017356879
RefSeq - XM_021477559
RefSeq - XM_021477560
swissprot - F1QIS3
swissprot - E7F4H1
ZFIN ID - ZDB-GENE-070501-1
Ensembl - ENSDARG00000007370
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 DYSFENSGALG00000016105Gallus gallus
 DYSFENSG00000135636Homo sapiens
 DysfENSMUSG00000033788Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
myof / myoferlin / Q69ZN7* / Q9NZM1*ENSDARG0000000611252
myofl / myoferlin like / MYOF* / Q9NZM1* / myoferlin*ENSDARG0000001712850
otofa / Q5SPC5 / otoferlin a / OTOF* / Q9HC10* / otoferlin* / otoferlin isoform 3 *ENSDARG0000003083231
fer1l6 / fer-1-like family member 6 / Q2WGJ9*ENSDARG0000001931629
otofb / otoferlin b / OTOF* / Q9HC10* / otoferlin* / otoferlin isoform 3 *ENSDARG0000002058129
fer1l4 / fer-1-like family member 4ENSDARG0000007695228


Protein motifs (from Interpro)
Interpro ID Name
 IPR000008  C2 domain
 IPR006614  Peroxin/Ferlin domain
 IPR012560  Ferlin A-domain
 IPR012561  Ferlin B-domain
 IPR012968  FerIin domain
 IPR029998  Dysferlin
 IPR032362  Ferlin, C-terminal domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001778 plasma membrane repair IMP
 biological_processGO:0033292 T-tubule organization IMP
 biological_processGO:0048644 muscle organ morphogenesis IMP
 biological_processGO:0071433 cell wall repair IMP
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0030315 T-tubule IDA
 cellular_componentGO:0042383 sarcolemma IDA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000114 heart heart edematous , abnormal
Show

 ZFA:0000155 somite somite anatomical compartment boundary shape , abnormal
Show

 ZFA:0001115 trunk trunk curved , abnormal
Show

 ZFA:0005145 muscle muscle refractivity , abnormal
muscle myofibril misaligned with muscle myofibril, abnormal
muscle damaged , abnormal
muscle myofibril misrouted , abnormal
muscle T-tubule broken , abnormal
muscle T-tubule misaligned with muscle T-tubule, abnormal
Show

 ZFA:0009114 muscle cell muscle cell cytoplasmic vesicle accumulation muscle sarcolemma, abnormal
Show

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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