ENSDARG00000009387


Danio rerio

Features
Gene ID: ENSDARG00000009387
  
Biological name :robo4
  
Synonyms : robo4 / roundabout, axon guidance receptor, homolog 4 (Drosophila)
  
Possible biological names infered from orthology : Q8WZ75 / roundabout guidance receptor 4
  
Species: Danio rerio
  
Chr. number: 10
Strand: 1
Band:
Gene start: 31244619
Gene end: 31284790
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSDARP00000112841
Ensembl peptide - ENSDARP00000156228
Ensembl peptide - ENSDARP00000156487
NCBI entrez gene - 560765     See in Manteia.
swissprot - F1RE66
ZFIN ID - ZDB-GENE-020809-1
Ensembl - ENSDARG00000009387
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ENSGALG00000043088Gallus gallus
 ROBO4ENSG00000154133Homo sapiens
 Robo4ENSMUSG00000032125Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
robo1 / roundabout, axon guidance receptor, homolog 1 (Drosophila) / Q9Y6N7* / roundabout guidance receptor 1*ENSDARG0000002678431
robo3 / roundabout, axon guidance receptor, homolog 3 (Drosophila) / Q96MS0* / roundabout guidance receptor 3*ENSDARG0000000564524
robo2 / roundabout, axon guidance receptor, homolog 2 (Drosophila)ENSDARG0000001489120
cdon / cell adhesion associated, oncogene regulated / Q32MD9* / Q4KMG0* / Cell adhesion molecule-related/down-regulated by oncos *ENSDARG0000006132813
boc / BOC cell adhesion associated, oncogene regulated / Q9BWV1*ENSDARG0000007433512
ncam1b / neural cell adhesion molecule 1b / NCAM1* / P13591* / neural cell adhesion molecule 1* / neural cell adhesion molecule 1 isoform 3 *ENSDARG000000072209
ncam2 / neural cell adhesion molecule 2 / O15394* / O35136*ENSDARG000000174668
ncam1a / neural cell adhesion molecule 1a / NCAM1* / P13591* / neural cell adhesion molecule 1* / neural cell adhesion molecule 1 isoform 3 *ENSDARG000000561818
ncam3 / neural cell adhesion molecule 3ENSDARG000000895868
zgc:77784 / ROBO3* / Q96MS0* / roundabout guidance receptor 3*ENSDARG000000426466
robo2 / roundabout, axon guidance receptor, homolog 2 (Drosophila)ENSDARG000000783665
BX908388.2ENSDARG000001137745


Protein motifs (from Interpro)
Interpro ID Name
 IPR003598  Immunoglobulin subtype 2
 IPR003599  Immunoglobulin subtype
 IPR003961  Fibronectin type III
 IPR007110  Immunoglobulin-like domain
 IPR013098  Immunoglobulin I-set
 IPR013783  Immunoglobulin-like fold
 IPR032986  Roundabout homologue 1


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001525 angiogenesis IMP
 biological_processGO:0001954 positive regulation of cell-matrix adhesion IDA
 biological_processGO:0030032 lamellipodium assembly IDA
 biological_processGO:0030334 regulation of cell migration IMP
 biological_processGO:0035022 positive regulation of Rac protein signal transduction IMP
 biological_processGO:0043542 endothelial cell migration IDA
 biological_processGO:0046847 filopodium assembly IDA
 biological_processGO:0051057 positive regulation of small GTPase mediated signal transduction IMP
 cellular_componentGO:0016021 integral component of membrane ISS
 cellular_componentGO:0031226 intrinsic component of plasma membrane IDA
 molecular_functionGO:0003674 molecular_function ND


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0001319 myocardium myocardium cell malformed , abnormal
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 ZFA:0001320 endocardium endocardium cell malformed , abnormal
Show

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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