ENSDARG00000011072


Danio rerio

Features
Gene ID: ENSDARG00000011072
  
Biological name :ddx11
  
Synonyms : ddx11 / DEAD/H (Asp-Glu-Ala-Asp/His) box helicase 11 / F1R345
  
Possible biological names infered from orthology : DEAD/H-box helicase 11 / Mus musculus DEAD/H (Asp-Glu-Ala-Asp/His) box helicase 11 (Ddx11), transcript variant 2, mRNA. / Q6AXC6 / Q96FC9
  
Species: Danio rerio
  
Chr. number: 18
Strand: -1
Band:
Gene start: 6502441
Gene end: 6534516
  
Corresponding Affymetrix probe sets: Dr.245.1.A1_at (Zebrafish Array)   NM_001007319_at (Zebrafish Genome Array with custom cdf files)   
  
Cross references: Ensembl peptide - ENSDARP00000025514
Ensembl peptide - ENSDARP00000153770
NCBI entrez gene - 492353     See in Manteia.
RefSeq - NM_001007319
RefSeq Peptide - NP_001007320
swissprot - F1R345
ZFIN ID - ZDB-GENE-041114-191
Ensembl - ENSDARG00000011072
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ENSGALG00000039636Gallus gallus
 DDX11ENSG00000013573Homo sapiens
 Ddx11ENSMUSG00000035842Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
rtel1 / regulator of telomere elongation helicase 1 / Q9NZ71* / Q0VGM9* / RTEL1-TNFRSF6B* / RTEL1-TNFRSF6B readthrough (NMD candidate)*ENSDARG0000003507423
brip1 / BRCA1 interacting protein C-terminal helicase 1 / Q5SXJ3* / Q9BX63* / Fanconi anemia group J protein homolog *ENSDARG0000007441023


Protein motifs (from Interpro)
Interpro ID Name
 IPR006554  Helicase-like, DEXD box c2 type
 IPR006555  ATP-dependent helicase, C-terminal
 IPR010614  DEAD2
 IPR013020  ATP-dependent helicase Rad3/Chl1-like
 IPR014013  Helicase superfamily 1/2, ATP-binding domain, DinG/Rad3-type
 IPR027417  P-loop containing nucleoside triphosphate hydrolase
 IPR028331  Probable ATP-dependent RNA helicase DDX11/DDX12


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006139 nucleobase-containing compound metabolic process IEA
 biological_processGO:0006260 DNA replication IEA
 biological_processGO:0006281 DNA repair IEA
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0006974 cellular response to DNA damage stimulus IEA
 biological_processGO:0007275 multicellular organism development IEA
 biological_processGO:0009303 rRNA transcription IMP
 biological_processGO:0032508 DNA duplex unwinding IEA
 biological_processGO:1901836 regulation of transcription of nucleolar large rRNA by RNA polymerase I IMP
 biological_processGO:1990700 nucleolar chromatin organization IMP
 cellular_componentGO:0000922 spindle pole IEA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005730 nucleolus IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005815 microtubule organizing center IEA
 cellular_componentGO:0005856 cytoskeleton IEA
 cellular_componentGO:0030496 midbody IEA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0003676 nucleic acid binding IEA
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0003723 RNA binding IEA
 molecular_functionGO:0004003 ATP-dependent DNA helicase activity IEA
 molecular_functionGO:0004386 helicase activity IEA
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0008026 ATP-dependent helicase activity IEA
 molecular_functionGO:0016787 hydrolase activity IEA
 molecular_functionGO:0016818 hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides IEA
 molecular_functionGO:0046872 metal ion binding IEA
 molecular_functionGO:0051536 iron-sulfur cluster binding IEA
 molecular_functionGO:0051539 4 iron, 4 sulfur cluster binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000107 eye eye decreased distance eye , abnormal
eye decreased size , abnormal
Show

 ZFA:0000547 mouth mouth decreased position , abnormal
mouth protruding , abnormal
Show

 ZFA:0001094 whole organism whole organism decreased length , abnormal
Show

 ZFA:0001114 head head anterior region increased length , abnormal
Show

 ZFA:0001115 trunk trunk curved caudal , abnormal
Show

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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