ENSDARG00000035074


Danio rerio

Features
Gene ID: ENSDARG00000035074
  
Biological name :rtel1
  
Synonyms : regulator of telomere elongation helicase 1 / rtel1
  
Possible biological names infered from orthology : Q0VGM9 / Q9NZ71 / RTEL1-TNFRSF6B / RTEL1-TNFRSF6B readthrough (NMD candidate)
  
Species: Danio rerio
  
Chr. number: 11
Strand: 1
Band:
Gene start: 12811906
Gene end: 12859263
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSDARP00000105420
NCBI entrez gene - 503732     See in Manteia.
RefSeq - NM_001013310
RefSeq - XM_009305892
RefSeq Peptide - NP_001013328
swissprot - F1QNW3
ZFIN ID - ZDB-GENE-050306-11
Ensembl - ENSDARG00000035074
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ENSGALG00000006123Gallus gallus
 RTEL1ENSG00000258366Homo sapiens
 RTEL1-TNFRSF6BENSG00000026036Homo sapiens
 Rtel1ENSMUSG00000038685Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
brip1 / BRCA1 interacting protein C-terminal helicase 1 / Q5SXJ3* / Q9BX63* / Fanconi anemia group J protein homolog *ENSDARG0000007441022
ddx11 / F1R345 / DEAD/H (Asp-Glu-Ala-Asp/His) box helicase 11 / Q6AXC6* / Q96FC9* / DEAD/H-box helicase 11* / Mus musculus DEAD/H (Asp-Glu-Ala-Asp/His) box helicase 11 (Ddx11), transcript v...ENSDARG0000001107217


Protein motifs (from Interpro)
Interpro ID Name
 IPR006554  Helicase-like, DEXD box c2 type
 IPR006555  ATP-dependent helicase, C-terminal
 IPR010614  DEAD2
 IPR013020  ATP-dependent helicase Rad3/Chl1-like
 IPR014001  Helicase superfamily 1/2, ATP-binding domain
 IPR014013  Helicase superfamily 1/2, ATP-binding domain, DinG/Rad3-type
 IPR027417  P-loop containing nucleoside triphosphate hydrolase
 IPR030845  Regulator of telomere elongation helicase 1


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000723 telomere maintenance IEA
 biological_processGO:0006139 nucleobase-containing compound metabolic process IEA
 biological_processGO:0006260 DNA replication IEA
 biological_processGO:0006281 DNA repair IEA
 biological_processGO:0006310 DNA recombination IEA
 biological_processGO:0006974 cellular response to DNA damage stimulus IEA
 biological_processGO:0010569 regulation of double-strand break repair via homologous recombination IEA
 biological_processGO:0032508 DNA duplex unwinding IEA
 cellular_componentGO:0005634 nucleus IEA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0003676 nucleic acid binding IEA
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0004003 ATP-dependent DNA helicase activity IEA
 molecular_functionGO:0004386 helicase activity IEA
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0008026 ATP-dependent helicase activity IEA
 molecular_functionGO:0016787 hydrolase activity IEA
 molecular_functionGO:0016818 hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides IEA
 molecular_functionGO:0046872 metal ion binding IEA
 molecular_functionGO:0051536 iron-sulfur cluster binding IEA
 molecular_functionGO:0051539 4 iron, 4 sulfur cluster binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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