ENSDARG00000011618


Danio rerio

Features
Gene ID: ENSDARG00000011618
  
Biological name :slc26a2
  
Synonyms : slc26a2 / solute carrier family 26 (anion exchanger), member 2
  
Possible biological names infered from orthology : P50443 / Q62273 / solute carrier family 26 member 2 / Sulfate transporter
  
Species: Danio rerio
  
Chr. number: 14
Strand: -1
Band:
Gene start: 25438015
Gene end: 25452503
  
Corresponding Affymetrix probe sets: Dr.25513.1.A1_at (Zebrafish Array)   
  
Cross references: Ensembl peptide - ENSDARP00000124111
Ensembl peptide - ENSDARP00000148044
NCBI entrez gene - 557046     See in Manteia.
swissprot - E7F9I7
ZFIN ID - ZDB-GENE-030717-3
Ensembl - ENSDARG00000011618
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 SLC26A2ENSGALG00000001239Gallus gallus
 P50443ENSG00000155850Homo sapiens
 Q62273ENSMUSG00000034320Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
slc26a1 / solute carrier family 26 (anion exchanger), member 1 / Q9H2B4* / P58735* / solute carrier family 26 member 1* / solute carrier family 26 (sulfate transporter), member 1*ENSDARG0000002983248
slc26a3.2 / solute carrier family 26 (anion exchanger), member 3, tandem duplicate 2 / P40879* / Q9WVC8* / SLC26A3* / Chloride anion exchanger * / solute carrier family 26 member 3*ENSDARG0000000361534
slc26a5 / solute carrier family 26 (anion exchanger), member 5 / Q99NH7* / P58743* / Prestin * / solute carrier family 26 member 5*ENSDARG0000002242434
slc26a10 / solute carrier family 26, member 10 / Q8NG04*ENSDARG0000007880034
slc26a6l / solute carrier family 26, member 6, like / Q9BXS9* / SLC26A6* / solute carrier family 26 member 6*ENSDARG0000005412733
slc26a6 / solute carrier family 26, member 6 / Q9BXS9*ENSDARG0000005583533
slc26a3.1 / solute carrier family 26 (anion exchanger), member 3 / P40879* / Q9WVC8* / SLC26A3* / Chloride anion exchanger * / solute carrier family 26 member 3*ENSDARG0000000737132
si:ch211-117c9.2 / Q9BXS9* / SLC26A6* / solute carrier family 26 member 6*ENSDARG0000005873832
slc26a4 / solute carrier family 26 (anion exchanger), member 4 / Q9R155* / O43511* / Pendrin * / solute carrier family 26 member 4*ENSDARG0000006943132
slc26a6 / solute carrier family 26, member 6 / Q9BXS9*ENSDARG0000009729228


Protein motifs (from Interpro)
Interpro ID Name
 IPR001902  SLC26A/SulP transporter
 IPR002645  STAS domain
 IPR011547  SLC26A/SulP transporter domain
 IPR018045  Sulphate anion transporter, conserved site
 IPR030280  Solute carrier family 26 member 2


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001503 ossification IEA
 biological_processGO:0006811 ion transport IEA
 biological_processGO:0007605 sensory perception of sound IMP
 biological_processGO:0008272 sulfate transport IEA
 biological_processGO:0015701 bicarbonate transport IBA
 biological_processGO:0019532 oxalate transport IEA
 biological_processGO:0032474 otolith morphogenesis IMP
 biological_processGO:0036269 swimming behavior IMP
 biological_processGO:0042391 regulation of membrane potential IBA
 biological_processGO:0048884 neuromast development IMP
 biological_processGO:0051453 regulation of intracellular pH IBA
 biological_processGO:0055085 transmembrane transport IEA
 biological_processGO:0060117 auditory receptor cell development IMP
 biological_processGO:1902358 sulfate transmembrane transport IEA
 biological_processGO:1902476 chloride transmembrane transport IBA
 cellular_componentGO:0005887 integral component of plasma membrane IBA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0005254 chloride channel activity IBA
 molecular_functionGO:0008271 secondary active sulfate transmembrane transporter activity IEA
 molecular_functionGO:0015106 bicarbonate transmembrane transporter activity IBA
 molecular_functionGO:0015116 sulfate transmembrane transporter activity IBA
 molecular_functionGO:0015301 anion:anion antiporter activity IBA
 molecular_functionGO:0019531 oxalate transmembrane transporter activity IBA


Pathways (from Reactome)
Pathway description
Transport and synthesis of PAPS
Multifunctional anion exchangers


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000431 semicircular canal semicircular canal malformed , abnormal
Show

 ZFA:0000944 posterior lateral line posterior lateral line neuromast hair cell apoptotic , abnormal
Show

 ZFA:0001469 lateral line lateral line neuromast decreased amount , abnormal
lateral line neuromast hair cell decreased amount , abnormal
Show

 ZFA:0001470 anterior lateral line anterior lateral line neuromast hair cell apoptotic , abnormal
Show

 ZFA:0001617 otolith otolith amount , abnormal
otolith decreased size , abnormal
otolith mislocalised , abnormal
otolith fused with otolith , abnormal
Show

 ZFA:0009121 auditory receptor cell auditory receptor cell stereocilium decreased amount , abnormal
Show

 ZFA:0009149 Mauthner neuron Mauthner neuron excitatory postsynaptic potential amplitude , abnormal
Show

 ZFA:0009367 neuromast hair cell neuromast hair cell disorganized , abnormal
neuromast hair cell decreased amount , abnormal
Show

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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