Manteia

ENSDARG00000012177

Danio rerio

Features

Gene ID:	ENSDARG00000012177

Biological name :	rab4b

Synonyms :	rab4b / RAB4B, member RAS oncogene family

Possible biological names infered from orthology :	P61018 / Q91ZR1 / RAB4B-EGLN2 / RAB4B-EGLN2 readthrough (NMD candidate)

Species:	Danio rerio

Chr. number:	15
Strand:	-1
Band:
Gene start:	8813755
Gene end:	8856785

Corresponding Affymetrix probe sets:	Dr.15999.1.A1_at (Zebrafish Array) NM_001004002_at (Zebrafish Genome Array with custom cdf files)

Cross references:	Ensembl peptide - ENSDARP00000020980 Ensembl peptide - ENSDARP00000155726 NCBI entrez gene - 445498 See in Manteia. RefSeq - NM_001004002 RefSeq Peptide - NP_001004002 swissprot - G1K2H7 ZFIN ID - ZDB-GENE-040822-15 Ensembl - ENSDARG00000012177

See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed

Ortholog prediction (from Ensembl)

Ortholog name	ID	Species
RAB4B	ENSG00000167578	Homo sapiens
RAB4B-EGLN2	ENSG00000171570	Homo sapiens
Rab4b	ENSMUSG00000053291	Mus musculus

Paralog prediction (from Ensembl)

Paralog name	ID	Similarity(%)
rab4a / Q6PHI9 / RAB4a, member RAS oncogene family / P56371* / P20338* / Ras-related protein Rab-4A *	ENSDARG00000019144	87
rab14l / RAB14, member RAS oncogene family, like	ENSDARG00000035188	59
rab14 / RAB14, member RAS oncogene family / P61106* / Q91V41*	ENSDARG00000074246	59
rab2a / RAB2A, member RAS oncogene family / P53994* / P61019* / Ras-related protein Rab-2A *	ENSDARG00000020261	52
rab11ba / RAB11B, member RAS oncogene family, a / RAB11B* / P46638* / Q15907* / RAB11B, member RAS oncogene family*	ENSDARG00000041878	47
rab11bb / RAB11B, member RAS oncogene family, b / RAB11B* / P46638* / Q15907* / RAB11B, member RAS oncogene family*	ENSDARG00000090086	47
rab11a / RAB11a, member RAS oncogene family	ENSDARG00000041450	46
rab11al / RAB11a, member RAS oncogene family, like	ENSDARG00000014340	45
rab25a / RAB25, member RAS oncogene family a / RAB25* / Q9WTL2* / P57735* / RAB25, member RAS oncogene family*	ENSDARG00000058800	45
rab25b / RAB25, member RAS oncogene family b / RAB25* / P57735* / RAB25, member RAS oncogene family*	ENSDARG00000052954	43
rab39ba / RAB39B, member RAS oncogene family a / RAB39B* / Q8BHC1* / Q96DA2* / RAB39B, member RAS oncogene family*	ENSDARG00000019312	40
rab39bb / RAB39B, member RAS oncogene family b / RAB39B* / Q8BHC1* / Q96DA2* / RAB39B, member RAS oncogene family*	ENSDARG00000036501	40
rab18a / RAB18A, member RAS oncogene family / RAB18* / Q9NP72* / P35293* / RAB18, member RAS oncogene family*	ENSDARG00000055291	37
Q6DHC1 / rab18b / RAB18B, member RAS oncogene family / RAB18* / Q9NP72* / P35293* / RAB18, member RAS oncogene family*	ENSDARG00000098344	37
rab42a / RAB42, member RAS oncogene family a	ENSDARG00000034215	36
rab42b / RAB42, member RAS oncogene family	ENSDARG00000101170	35
si:dkey-34d22.2	ENSDARG00000100379	34
CU571310.1 / RAB42* / Q8N4Z0* / RAB42, member RAS oncogene family*	ENSDARG00000102580	29
si:dkey-34d22.5	ENSDARG00000104865	29
si:ch211-247i17.1	ENSDARG00000076727	20

Protein motifs (from Interpro)

Interpro ID	Name
IPR001806	Small GTPase superfamily
IPR005225	Small GTP-binding protein domain
IPR027417	P-loop containing nucleoside triphosphate hydrolase

Gene Ontology (GO)

Type	GO ID	Term	Ev.Code
molecular_function	GO:0003924	GTPase activity	IEA
molecular_function	GO:0005525	GTP binding	IEA

Pathways (from Reactome)

Pathway description

Neutrophil degranulation

RAB geranylgeranylation

MET receptor recycling

Phenotype (from MGI, Zfin or HPO)

Phenotype

Definition

Genetic BG

No match

Interacting proteins (from Reactome)

Interactor ID

Name

Interaction type

No match

0 s.

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		© Olivier Tassy / Olivier Pourquie 2007-2025 contact: otassy@igbmc.fr