ENSDARG00000012422


Danio rerio

Features
Gene ID: ENSDARG00000012422
  
Biological name :col11a2
  
Synonyms : col11a2 / collagen, type XI, alpha 2
  
Possible biological names infered from orthology : Collagen alpha-2(XI) chain / collagen type XI alpha 2 chain / P13942 / Q64739
  
Species: Danio rerio
  
Chr. number: 19
Strand: -1
Band:
Gene start: 7179740
Gene end: 7225206
  
Corresponding Affymetrix probe sets: Dr.19643.1.A1_at (Zebrafish Array)   DrAffx.2.30.S1_at (Zebrafish Array)   NM_001079992_at (Zebrafish Genome Array with custom cdf files)   
  
Cross references: Ensembl peptide - ENSDARP00000095569
Ensembl peptide - ENSDARP00000119303
Ensembl peptide - ENSDARP00000125963
Ensembl peptide - ENSDARP00000108486
NCBI entrez gene - 561679     See in Manteia.
RefSeq - NM_001079992
RefSeq - XM_009294049
RefSeq Peptide - NP_001073461
swissprot - F1R5X4
swissprot - E7F7J8
swissprot - F6NLZ6
swissprot - I3ISS1
ZFIN ID - ZDB-GENE-000208-23
Ensembl - ENSDARG00000012422
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 P13942ENSG00000204248Homo sapiens
 Q64739ENSMUSG00000024330Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
col5a1 / procollagen, type V, alpha 1 / O88207* / P20908* / Collagen alpha-1(V) chain * / collagen type V alpha 1 chain*ENSDARG0000001259367
col11a1a / collagen, type XI, alpha 1a / Q61245* / P12107* / COL11A1* / Collagen alpha-1(XI) chain * / collagen type XI alpha 1 chain*ENSDARG0000002616566
col11a1b / collagen, type XI, alpha 1b / Q61245* / P12107* / COL11A1* / Collagen alpha-1(XI) chain * / collagen type XI alpha 1 chain*ENSDARG0000000901463
col5a3a / collagen, type V, alpha 3a / COL5A3* / P25940* / collagen, type V, alpha 3* / collagen type V alpha 3 chain*ENSDARG0000009829458
col5a3b / collagen, type V, alpha 3b / COL5A3* / P25940* / collagen, type V, alpha 3* / collagen type V alpha 3 chain*ENSDARG0000010181654
col2a1a / collagen, type II, alpha 1a / COL2A1* / P02458* / P28481* / collagen type II alpha 1 chain* / Collagen alpha-1(II) chain Collagen alpha-1(II) chain Chondrocalcin*ENSDARG0000006909336
col1a1a / collagen, type I, alpha 1a / COL1A1* / P02452* / P11087* / Collagen alpha-1(I) chain * / collagen type I alpha 1 chain*ENSDARG0000001240535
col5a2b / collagen, type V, alpha 2b / COL5A2* / P05997* / Q3U962* / Collagen alpha-2(V) chain * / collagen type V alpha 2 chain*ENSDARG0000002484734
col5a2a / collagen, type V, alpha 2a / COL5A2* / P05997* / Q3U962* / Collagen alpha-2(V) chain * / collagen type V alpha 2 chain*ENSDARG0000003167834
col1a1b / collagen, type I, alpha 1b / COL1A1* / P02452* / P11087* / Collagen alpha-1(I) chain * / collagen type I alpha 1 chain*ENSDARG0000003580934
si:ch211-196i2.1ENSDARG0000000791233
col2a1b / collagen, type II, alpha 1b / COL2A1* / P02458* / collagen type II alpha 1 chain*ENSDARG0000001140733
col1a2 / collagen, type I, alpha 2 / Q01149* / P08123* / Collagen alpha-2(I) chain * / collagen type I alpha 2 chain*ENSDARG0000002000732
si:dkey-61l1.4ENSDARG0000009256727
si:dkey-21p1.3ENSDARG0000000229526
col27a1b / collagen, type XXVII, alpha 1b / Q8IZC6* / Q5QNQ9* / COL27A1* / Collagen alpha-1(XXVII) chain * / collagen type XXVII alpha 1 chain*ENSDARG0000009993022
si:ch1073-286c18.5ENSDARG000000985671


Protein motifs (from Interpro)
Interpro ID Name
 IPR000885  Fibrillar collagen, C-terminal
 IPR001791  Laminin G domain
 IPR008160  Collagen triple helix repeat
 IPR013320  Concanavalin A-like lectin/glucanase domain superfamily
 IPR014716  Fibrinogen, alpha/beta/gamma chain, C-terminal globular, subdomain 1


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0060536 cartilage morphogenesis IMP
 molecular_functionGO:0005201 extracellular matrix structural constituent IEA


Pathways (from Reactome)
Pathway description
Collagen degradation
Collagen biosynthesis and modifying enzymes
Assembly of collagen fibrils and other multimeric structures
Non-integrin membrane-ECM interactions
MET activates PTK2 signaling
Collagen chain trimerization


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000107 eye eye mislocalised , abnormal
Show

 ZFA:0000135 notochord notochord undulate , abnormal
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 ZFA:0000547 mouth mouth absent , abnormal
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 ZFA:0001114 head head decreased size , abnormal
head malformed , abnormal
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 ZFA:0001205 Meckel s cartilage Meckels cartilage decreased size , abnormal
Meckels cartilage mislocalised , abnormal
Meckels cartilage malformed , abnormal
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 ZFA:0001239 ceratobranchial 5 bone ceratobranchial 5 bone composition , abnormal
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 ZFA:0001306 pharyngeal arch pharyngeal arch aplastic , abnormal
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 ZFA:0001321 neurocranial trabecula neurocranial trabecula decreased size , abnormal
neurocranial trabecula malformed , abnormal
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 ZFA:0001400 ceratohyal cartilage ceratohyal cartilage mislocalised , abnormal
ceratohyal cartilage malformed , abnormal
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 ZFA:0001405 ethmoid cartilage ethmoid cartilage decreased size , abnormal
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 ZFA:0001458 cranial cartilage cranial cartilage disorganized , abnormal
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 ZFA:0001460 pharyngeal arch cartilage pharyngeal arch cartilage disorganized , abnormal
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 ZFA:0001516 ceratobranchial cartilage ceratobranchial cartilage decreased size , abnormal
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 ZFA:0001633 perichordal connective tissue perichordal connective tissue morphology , abnormal
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 ZFA:0009084 chondrocyte chondrocyte disorganized , abnormal
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Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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