ENSDARG00000013414


Danio rerio

Features
Gene ID: ENSDARG00000013414
  
Biological name :lin7a
  
Synonyms : lin7a / lin-7 homolog A (C. elegans)
  
Possible biological names infered from orthology : lin-7 homolog A, crumbs cell polarity complex component / O14910 / Q8JZS0
  
Species: Danio rerio
  
Chr. number: 4
Strand: -1
Band:
Gene start: 21751762
Gene end: 21851473
  
Corresponding Affymetrix probe sets: Dr.11345.1.A1_at (Zebrafish Array)   
  
Cross references: Ensembl peptide - ENSDARP00000022617
NCBI entrez gene - 393682     See in Manteia.
RefSeq - XM_005164866
RefSeq Peptide - NP_957003
swissprot - Q6PC63
ZFIN ID - ZDB-GENE-040426-1665
Ensembl - ENSDARG00000013414
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 LIN7AENSGALG00000010939Gallus gallus
 LIN7AENSG00000111052Homo sapiens
 Lin7aENSMUSG00000019906Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
lin7c / lin-7 homolog C (C. elegans)ENSDARG0000002732271
lin7b / lin-7 homolog B (C. elegans) / B * / O88951* / Q9HAP6* / lin-7 homolog B, crumbs cell polarity complex component*ENSDARG0000003793271
sntb1 / syntrophin, basic 1 / Q99L88* / Q13884* / syntrophin beta 1* / Beta-1-syntrophin *ENSDARG0000004172928
gopc / golgi-associated PDZ and coiled-coil motif containing / Q8BH60* / Q9HD26* / AL132671.2*ENSDARG0000002311725
sntb2 / syntrophin, beta 2 / Q13425* / Q61235* / syntrophin, basic 2*ENSDARG0000005176323
SNTA1 / syntrophin alpha 1 / Q13424*ENSDARG0000009842022
sntg2 / syntrophin, gamma 2 / Q925E0* / Q9NY99* / Gamma-2-syntrophin *ENSDARG0000010166022
sntg1 / syntrophin, gamma 1 / Q9NSN8*ENSDARG0000006183221


Protein motifs (from Interpro)
Interpro ID Name
 IPR001478  PDZ domain
 IPR004172  L27 domain
 IPR014775  L27 domain, C-terminal
 IPR017365  Protein lin-7


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006887 exocytosis IEA
 biological_processGO:0007269 neurotransmitter secretion IEA
 biological_processGO:0015031 protein transport IEA
 biological_processGO:0045199 maintenance of epithelial cell apical/basal polarity IBA
 biological_processGO:1903361 protein localization to basolateral plasma membrane IBA
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0005911 cell-cell junction IBA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016323 basolateral plasma membrane IEA
 cellular_componentGO:0030054 cell junction IEA
 cellular_componentGO:0045202 synapse IBA
 cellular_componentGO:0097025 MPP7-DLG1-LIN7 complex IEA
 cellular_componentGO:0098793 presynapse IEA
 molecular_functionGO:0097016 L27 domain binding IEA


Pathways (from Reactome)
Pathway description
Dopamine Neurotransmitter Release Cycle


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSDARG00000074328 apba1b / amyloid beta (A4) precursor protein-binding, family A, member 1b / APBA1* / B2RUJ5* / Q02410* / Amyloid-beta A4 protein-binding family A member 1 * / amyloid beta precursor protein...  / complex / reaction
 ENSDARG00000103848 apba1a / amyloid beta (A4) precursor protein-binding, family A, member 1a / APBA1* / B2RUJ5* / Q02410* / Amyloid-beta A4 protein-binding family A member 1 * / amyloid beta precursor protein...  / complex / reaction






 

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