ENSDARG00000013858


Danio rerio

Features
Gene ID: ENSDARG00000013858
  
Biological name :cdc14aa
  
Synonyms : cdc14aa / cell division cycle 14Aa
  
Possible biological names infered from orthology : CDC14A / cell division cycle 14A / Dual specificity protein phosphatase CDC14A / Q6GQT0 / Q9UNH5
  
Species: Danio rerio
  
Chr. number: 2
Strand: 1
Band:
Gene start: 7075220
Gene end: 7105532
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSDARP00000010568
swissprot - A8DZH6
ZFIN ID - ZDB-GENE-040426-1214
Ensembl - ENSDARG00000013858
  
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 CDC14AENSGALG00000005248Gallus gallus
 CDC14AENSG00000079335Homo sapiens
 Cdc14aENSMUSG00000033502Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
cdc14ab / A0A0R4IVA4 / cell division cycle 14Ab / CDC14A* / Q6GQT0* / Q9UNH5* / cell division cycle 14A* / Dual specificity protein phosphatase CDC14A *ENSDARG0000005701657
cdc14b / cell division cycle 14B / O60729* / Q6PFY9* / Dual specificity protein phosphatase CDC14B *ENSDARG0000002148343
dusp23a / dual specificity phosphatase 23a / Q9BVJ7* / DUSP23* / Q6NT99* / dual specificity phosphatase 23* / Dual specificity protein phosphatase 23 *ENSDARG000000098447
dusp23b / dual specificity phosphatase 23b / Q9BVJ7* / DUSP23* / Q6NT99* / dual specificity phosphatase 23* / Dual specificity protein phosphatase 23 *ENSDARG000000892457


Protein motifs (from Interpro)
Interpro ID Name
 IPR000340  Dual specificity phosphatase, catalytic domain
 IPR000387  Tyrosine specific protein phosphatases domain
 IPR016130  Protein-tyrosine phosphatase, active site
 IPR020422  Dual specificity protein phosphatase domain
 IPR026068  Dual specificity protein phosphatase CDC14A
 IPR029021  Protein-tyrosine phosphatase-like
 IPR029260  Dual specificity/tyrosine protein phosphatase, N-terminal


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006470 protein dephosphorylation IEA
 biological_processGO:0007096 regulation of exit from mitosis IBA
 biological_processGO:0016311 dephosphorylation IEA
 biological_processGO:0035335 peptidyl-tyrosine dephosphorylation IEA
 biological_processGO:0051256 mitotic spindle midzone assembly IBA
 biological_processGO:0060271 cilium assembly IMP
 biological_processGO:0071850 mitotic cell cycle arrest IBA
 cellular_componentGO:0000922 spindle pole IDA
 cellular_componentGO:0005634 nucleus IBA
 cellular_componentGO:0005737 cytoplasm IBA
 cellular_componentGO:0005813 centrosome IDA
 cellular_componentGO:0005819 spindle IDA
 cellular_componentGO:0072686 mitotic spindle IBA
 molecular_functionGO:0004722 protein serine/threonine phosphatase activity IBA
 molecular_functionGO:0004725 protein tyrosine phosphatase activity IBA
 molecular_functionGO:0008138 protein tyrosine/serine/threonine phosphatase activity IEA
 molecular_functionGO:0016791 phosphatase activity IEA


Pathways (from Reactome)
Pathway description
Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase
MAPK6/MAPK4 signaling


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000001 Kupffer s vesicle Kupffers vesicle motile cilium decreased length , abnormal
Kupffers vesicle cell decreased amount , abnormal
Kupffers vesicle motile cilium decreased amount , abnormal
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 ZFA:0000150 pronephric duct pronephric duct motile cilium decreased length , abnormal
Show

 ZFA:0000558 posterior macula posterior macula cilium length , abnormal
Show

 ZFA:0000678 hair cell anterior macula hair cell anterior macula kinocilium decreased length , abnormal
Show

 ZFA:0001094 whole organism whole organism curved ventral , abnormal
whole organism increased curvature , abnormal
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Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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