ENSDARG00000021483


Danio rerio

Features
Gene ID: ENSDARG00000021483
  
Biological name :cdc14b
  
Synonyms : cdc14b / cell division cycle 14B
  
Possible biological names infered from orthology : Dual specificity protein phosphatase CDC14B / O60729 / Q6PFY9
  
Species: Danio rerio
  
Chr. number: 8
Strand: -1
Band:
Gene start: 1222132
Gene end: 1267247
  
Corresponding Affymetrix probe sets: Dr.14635.1.A1_at (Zebrafish Array)   NM_200179_at (Zebrafish Genome Array with custom cdf files)   
  
Cross references: Ensembl peptide - ENSDARP00000124917
Ensembl peptide - ENSDARP00000125006
Ensembl peptide - ENSDARP00000154397
Ensembl peptide - ENSDARP00000123900
Ensembl peptide - ENSDARP00000124680
Ensembl peptide - ENSDARP00000124791
NCBI entrez gene - 393148     See in Manteia.
RefSeq - NM_200179
RefSeq - XM_005166673
RefSeq - XM_021478210
RefSeq Peptide - NP_956473
swissprot - F8W4L1
swissprot - F8W2B2
swissprot - F8W2M0
swissprot - F8W5R0
swissprot - F8W600
swissprot - Q7ZVN3
ZFIN ID - ZDB-GENE-040426-820
Ensembl - ENSDARG00000021483
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 CDC14BENSGALG00000012627Gallus gallus
 CDC14BENSG00000081377Homo sapiens
 Cdc14bENSMUSG00000033102Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
cdc14ab / A0A0R4IVA4 / cell division cycle 14Ab / CDC14A* / Q6GQT0* / Q9UNH5* / cell division cycle 14A* / Dual specificity protein phosphatase CDC14A *ENSDARG0000005701654
cdc14aa / cell division cycle 14Aa / CDC14A* / Q6GQT0* / Q9UNH5* / cell division cycle 14A* / Dual specificity protein phosphatase CDC14A *ENSDARG0000001385853
dusp23a / dual specificity phosphatase 23a / Q9BVJ7* / DUSP23* / Q6NT99* / dual specificity phosphatase 23* / Dual specificity protein phosphatase 23 *ENSDARG000000098449
dusp23b / dual specificity phosphatase 23b / Q9BVJ7* / DUSP23* / Q6NT99* / dual specificity phosphatase 23* / Dual specificity protein phosphatase 23 *ENSDARG000000892458


Protein motifs (from Interpro)
Interpro ID Name
 IPR000340  Dual specificity phosphatase, catalytic domain
 IPR000387  Tyrosine specific protein phosphatases domain
 IPR003595  Protein-tyrosine phosphatase, catalytic
 IPR016130  Protein-tyrosine phosphatase, active site
 IPR020422  Dual specificity protein phosphatase domain
 IPR029021  Protein-tyrosine phosphatase-like
 IPR029260  Dual specificity/tyrosine protein phosphatase, N-terminal


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006470 protein dephosphorylation IEA
 biological_processGO:0007096 regulation of exit from mitosis IBA
 biological_processGO:0016311 dephosphorylation IEA
 biological_processGO:0035335 peptidyl-tyrosine dephosphorylation IEA
 biological_processGO:0051256 mitotic spindle midzone assembly IBA
 biological_processGO:0051301 cell division IEA
 biological_processGO:0060271 cilium assembly IMP
 biological_processGO:0071850 mitotic cell cycle arrest IBA
 cellular_componentGO:0000793 condensed chromosome IDA
 cellular_componentGO:0000922 spindle pole IBA
 cellular_componentGO:0005730 nucleolus IDA
 cellular_componentGO:0005737 cytoplasm IBA
 cellular_componentGO:0005819 spindle IDA
 cellular_componentGO:0072686 mitotic spindle IBA
 molecular_functionGO:0004722 protein serine/threonine phosphatase activity IBA
 molecular_functionGO:0004725 protein tyrosine phosphatase activity IEA
 molecular_functionGO:0008138 protein tyrosine/serine/threonine phosphatase activity IEA
 molecular_functionGO:0016791 phosphatase activity IEA


Pathways (from Reactome)
Pathway description
MAPK6/MAPK4 signaling


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000001 Kupffer s vesicle Kupffers vesicle motile cilium decreased length , abnormal
Kupffers vesicle cilium decreased length , abnormal
Kupffers vesicle cilium decreased amount , abnormal
Kupffers vesicle cilium increased amount , abnormal
Show

 ZFA:0000008 brain brain hydrocephalic , abnormal
Show

 ZFA:0000054 pericardium pericardium edematous , abnormal
Show

 ZFA:0000150 pronephric duct pronephric duct cilium decreased length , abnormal
pronephric duct cilium decreased amount , abnormal
pronephric duct cilium increased length , abnormal
Show

 ZFA:0000151 pronephros pronephros cystic , abnormal
Show

 ZFA:0001094 whole organism whole organism decreased size , abnormal
whole organism increased curvature , abnormal
Show

 ZFA:0001117 post-vent region post-vent region curved ventral , abnormal
post-vent region curved dorsal , abnormal
Show

 ZFA:0007000 macula saccule macula saccule cilium decreased length , abnormal
macula saccule cilium decreased amount , abnormal
macula saccule cell decreased amount , abnormal
Show

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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