ENSDARG00000013968


Danio rerio

Features
Gene ID: ENSDARG00000013968
  
Biological name :psap
  
Synonyms : prosaposin / psap
  
Possible biological names infered from orthology : P07602 / prosaposin-like 1 / prosaposin like 1 (gene/pseudogene) / PSAPL1 / Q61207 / Q6NUJ1
  
Species: Danio rerio
  
Chr. number: 13
Strand: 1
Band:
Gene start: 5004924
Gene end: 5028964
  
Corresponding Affymetrix probe sets: Dr.1370.1.S1_at (Zebrafish Array)   NM_131883_at (Zebrafish Genome Array with custom cdf files)   
  
Cross references: Ensembl peptide - ENSDARP00000056294
Ensembl peptide - ENSDARP00000142376
Ensembl peptide - ENSDARP00000136693
Ensembl peptide - ENSDARP00000106362
NCBI entrez gene - 140811     See in Manteia.
RefSeq - NM_001309267
RefSeq - NM_131883
RefSeq Peptide - NP_001296196
RefSeq Peptide - NP_571958
swissprot - E7FCT1
swissprot - B8JI17
swissprot - A0A140LGJ7
swissprot - A0A0R4ILW2
ZFIN ID - ZDB-GENE-020108-1
Ensembl - ENSDARG00000013968
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ENSGALG00000004747Gallus gallus
 PSAPENSGALG00000004769Gallus gallus
 PSAPENSG00000197746Homo sapiens
 PSAPL1ENSG00000178597Homo sapiens
 PsapENSMUSG00000004207Mus musculus
 Psapl1ENSMUSG00000043430Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
sftpbb / surfactant protein Bb / SFTPB* / P07988* / surfactant protein B* / surfactant associated protein B*ENSDARG0000006756613
sftpba / surfactant protein Ba / SFTPB* / P07988* / surfactant protein B* / surfactant associated protein B*ENSDARG0000009470813


Protein motifs (from Interpro)
Interpro ID Name
 IPR003119  Saposin A-type domain
 IPR007856  Saposin-like type B, region 1
 IPR008138  Saposin B type, region 2
 IPR008139  Saposin B type domain
 IPR008373  Saposin
 IPR011001  Saposin-like
 IPR021165  Saposin, chordata


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006629 lipid metabolic process IEA
 biological_processGO:0006665 sphingolipid metabolic process IEA
 biological_processGO:0043085 positive regulation of catalytic activity IEA
 cellular_componentGO:0005615 extracellular space IBA
 cellular_componentGO:0005737 cytoplasm IBA
 cellular_componentGO:0005764 lysosome IEA
 molecular_functionGO:0001664 G-protein coupled receptor binding IBA
 molecular_functionGO:0008047 enzyme activator activity IBA


Pathways (from Reactome)
Pathway description
Platelet degranulation
Glycosphingolipid metabolism
Peptide ligand-binding receptors
G alpha (i) signalling events
Neutrophil degranulation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSDARG00000033296 gpr37b / G protein-coupled receptor 37b / GPR37* / O15354* / Q9QY42* / Prosaposin receptor GPR37 * / G protein-coupled receptor 37*  / complex / reaction
 ENSDARG00000076058 gba / glucosidase, beta, acid / P04062* / P17439* / Glucosylceramidase * / glucosylceramidase beta*  / complex
 ENSDARG00000074563 gpr37a / G protein-coupled receptor 37a / GPR37* / O15354* / Q9QY42* / Prosaposin receptor GPR37 * / G protein-coupled receptor 37*  / complex / reaction
 ENSDARG00000056774 gpr37l1b / G protein-coupled receptor 37 like 1b / Q99JG2* / O60883* / GPR37L1* / G protein-coupled receptor 37 like 1*  / complex / reaction






 

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