ENSDARG00000014201


Danio rerio

Features
Gene ID: ENSDARG00000014201
  
Biological name :otpa
  
Synonyms : orthopedia homeobox a / otpa
  
Possible biological names infered from orthology : Homeobox protein orthopedia / O09113 / orthopedia homeobox / OTP / Q5XKR4
  
Species: Danio rerio
  
Chr. number: 21
Strand: 1
Band:
Gene start: 7582036
Gene end: 7586992
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSDARP00000015517
Ensembl peptide - ENSDARP00000122571
NCBI entrez gene - 560759     See in Manteia.
RefSeq - NM_001128703
RefSeq Peptide - NP_001122175
swissprot - E9QGH0
swissprot - B3DGA5
ZFIN ID - ZDB-GENE-070216-1
Ensembl - ENSDARG00000014201
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 OTPENSGALG00000026744Gallus gallus
 OTPENSG00000171540Homo sapiens
 OtpENSMUSG00000021685Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
otpb / Q6DGH9 / orthopedia homeobox b / OTP* / O09113* / Q5XKR4* / orthopedia homeobox* / Homeobox protein orthopedia *ENSDARG0000005837983
shox2 / short stature homeobox 2 / O60902* / P70390*ENSDARG0000007571321
shox / short stature homeobox / O15266*ENSDARG0000002589120


Protein motifs (from Interpro)
Interpro ID Name
 IPR000047  Helix-turn-helix motif
 IPR001356  Homeobox domain
 IPR003654  OAR domain
 IPR009057  Homeobox-like domain superfamily
 IPR017970  Homeobox, conserved site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0007275 multicellular organism development IEA
 biological_processGO:0007632 visual behavior IMP
 biological_processGO:0021522 spinal cord motor neuron differentiation IMP
 biological_processGO:0021767 mammillary body development IGI
 biological_processGO:0021884 forebrain neuron development IMP
 biological_processGO:0030182 neuron differentiation IMP
 biological_processGO:0035176 social behavior IMP
 biological_processGO:0071542 dopaminergic neuron differentiation IMP
 cellular_componentGO:0005634 nucleus IEA
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0043565 sequence-specific DNA binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000032 hypothalamus hypothalamus dopaminergic neuron decreased amount , abnormal
Show

 ZFA:0000075 spinal cord spinal cord motor neuron decreased amount , abnormal
Show

 ZFA:0000470 preoptic area preoptic area neurosecretory neuron increased amount , abnormal
preoptic area neurosecretory neuron increased distribution , abnormal
Show

 ZFA:0000633 caudal tuberculum caudal tuberculum increased amount , abnormal
caudal tuberculum dopaminergic neuron decreased amount , abnormal
caudal tuberculum decreased distribution , abnormal
caudal tuberculum decreased amount , abnormal
Show

 ZFA:0009301 dopaminergic neuron dopaminergic neuron decreased amount , abnormal
Show

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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