ENSDARG00000014657


Danio rerio

Features
Gene ID: ENSDARG00000014657
  
Biological name :zgc:171731
  
Synonyms : zgc:171731
  
Possible biological names infered from orthology : CASP1 / CASP12 / CASP4 / CASP5 / caspase 1 / Caspase-12 / caspase 12 (gene/pseudogene) / Caspase-1 Caspase-1 subunit p20 Caspase-1 subunit p10 / caspase 4 / Caspase-4 Caspase-4 subunit p10 Caspase-4 subunit p20 / caspase 5 / O08736 / P29452 / P29466 / P49662 / P51878 / P70343 / Q6UXS9
  
Species: Danio rerio
  
Chr. number: 7
Strand: 1
Band:
Gene start: 19600262
Gene end: 19604900
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSDARP00000008601
NCBI entrez gene - 563034     See in Manteia.
RefSeq - NM_001109712
RefSeq Peptide - NP_001103182
swissprot - F1R234
ZFIN ID - ZDB-GENE-071004-27
Ensembl - ENSDARG00000014657
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ENSGALG00000001049Gallus gallus
 CASP1ENSG00000137752Homo sapiens
 CASP12ENSG00000204403Homo sapiens
 CASP4ENSG00000196954Homo sapiens
 CASP5ENSG00000137757Homo sapiens
 Casp1ENSMUSG00000025888Mus musculus
 Casp12ENSMUSG00000025887Mus musculus
 Casp4ENSMUSG00000033538Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
caspa / caspase a / CASP4* / CASP5* / CASP1* / Q6UXS9* / CASP12* / O08736* / P29452* / P29466* / P49662* / P51878* / P70343* / caspase 4* / caspase 1* / caspase 5* / Caspase-12 * / caspase ...ENSDARG0000000816532
caspb / caspase b / CASP4* / CASP5* / CASP1* / Q6UXS9* / CASP12* / O08736* / P29452* / P29466* / P49662* / P51878* / P70343* / caspase 5* / caspase 4* / caspase 1* / Caspase-12 * / caspase ...ENSDARG0000005203928
caspbl / caspase b, like / CASP4* / CASP5* / CASP1* / Q6UXS9* / CASP12* / O08736* / P29452* / P29466* / P49662* / P51878* / P70343* / caspase 5* / caspase 4* / caspase 1* / Caspase-12 * / c...ENSDARG0000009443328


Protein motifs (from Interpro)
Interpro ID Name
 IPR001309  Peptidase C14, p20 domain
 IPR002138  Peptidase C14, caspase non-catalytic subunit p10
 IPR015917  Peptidase C14A, caspase catalytic domain
 IPR016129  Peptidase family C14A, His active site
 IPR029030  Caspase-like domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006508 proteolysis IEA
 biological_processGO:0006915 apoptotic process IEA
 biological_processGO:0050727 regulation of inflammatory response IBA
 cellular_componentGO:0072557 IPAF inflammasome complex IBA
 cellular_componentGO:0072559 NLRP3 inflammasome complex IBA
 cellular_componentGO:0097169 AIM2 inflammasome complex IBA
 molecular_functionGO:0004197 cysteine-type endopeptidase activity IEA
 molecular_functionGO:0008234 cysteine-type peptidase activity IEA
 molecular_functionGO:0097153 cysteine-type endopeptidase activity involved in apoptotic process IBA


Pathways (from Reactome)
Pathway description
NOD1/2 Signaling Pathway
Interleukin-1 processing


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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