ENSDARG00000018266
Danio rerio mthfd1a domain activity formate-tetrahydrofolate ligase nad p -binding catalytic fthfs conserved site p-loop containing nucleoside triphosphate hydrolase oxidation-reduction process methylenetetrahydrofolate nadp atp binding metabolism folate pterines
Features Gene ID: ENSDARG00000018266 Biological name :mthfd1a Synonyms : methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1a, methenyltetrahydrofolate cyclohydrolase, formyltetrahydrofolate synthetase / mthfd1a Possible biological names infered from orthology : methylenetetrahydrofolate dehydrogenase, cyclohydrolase and formyltetrahydrofolate synthetase 1 / methylenetetrahydrofolate dehydrogenase (NADP+ dependent), methenyltetrahydrofolate cyclohydrolase, formyltetrahydrofolate synthase / MTHFD1 / P11586 / Q922D8 Species: Danio rerio Chr. number: 20 Strand: 1 Band: Gene start: 27646772 Gene end: 27687457 Corresponding Affymetrix probe sets: Cross references: Ensembl peptide - ENSDARP00000120805 Ensembl peptide - ENSDARP00000146429 Ensembl peptide - ENSDARP00000150792 NCBI entrez gene - 567587
See in Manteia .
swissprot - Q5RIH2 ZFIN ID - ZDB-GENE-041001-127 Ensembl - ENSDARG00000018266
See expression report in BioGPS See gene description in Wikigenes See co-cited genes in PubMed Ortholog prediction (from Ensembl )
Paralog prediction (from Ensembl ) mthfd1b / methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1b / Q922D8* / MTHFD1* / P11586* / methylenetetrahydrofolate dehydrogenase, cyclohydrolase and formyltetrahydrofolate syn... ENSDARG00000040492 61 mthfd1l / methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1 like / Q3V3R1* / Q6UB35* ENSDARG00000042221 39
Protein motifs (from Interpro ) IPR000559 Formate-tetrahydrofolate ligase, FTHFS IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase IPR016040 NAD(P)-binding domain IPR020630 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain IPR020631 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain IPR020867 Tetrahydrofolate dehydrogenase/cyclohydrolase, conserved site IPR027417 P-loop containing nucleoside triphosphate hydrolase
Gene Ontology (GO ) oxidation-reduction process oxidation-reduction process oxidation-reduction process oxidation-reduction process oxidation-reduction process oxidation-reduction process oxidation-reduction process oxidation-reduction process oxidation-reduction process oxidation-reduction process oxidation-reduction processoxidation-reduction process ligase activity oxidoreductase activity ion binding carbohydrate derivative binding organic cyclic compound binding heterocyclic compound binding small molecule binding drug binding ligase activity oxidoreductase activity ion binding carbohydrate derivative binding organic cyclic compound binding heterocyclic compound binding small molecule binding drug binding ligase activity oxidoreductase activity ion binding carbohydrate derivative binding organic cyclic compound binding heterocyclic compound binding small molecule binding drug binding ligase activity oxidoreductase activity ion binding carbohydrate derivative binding organic cyclic compound binding heterocyclic compound binding small molecule binding drug binding ligase activity oxidoreductase activity ion binding carbohydrate derivative binding organic cyclic compound binding heterocyclic compound binding small molecule binding drug binding ligase activity oxidoreductase activity ion binding carbohydrate derivative binding organic cyclic compound binding heterocyclic compound binding small molecule binding drug binding ligase activity oxidoreductase activity ion binding carbohydrate derivative binding organic cyclic compound binding heterocyclic compound binding small molecule binding drug binding ligase activity oxidoreductase activity ion binding carbohydrate derivative binding organic cyclic compound binding heterocyclic compound binding small molecule binding drug binding ligase activity oxidoreductase activity ion binding carbohydrate derivative binding organic cyclic compound binding heterocyclic compound binding small molecule binding drug binding ligase activity oxidoreductase activity ion binding carbohydrate derivative binding organic cyclic compound binding heterocyclic compound binding small molecule binding drug binding ligase activityligase activity oxidoreductase acoxidoreductase activity ion bindingion binding carbohydrate dericarbohydrate derivative binding organic cyclic coorganic cyclic compound binding heterocyclic compheterocyclic compound binding small molecule bismall molecule binding drug bindingdrug binding
Pathways (from Reactome )
Phenotype (from MGI , Zfin or HPO )
No match
Interacting proteins (from Reactome ) ENSDARG00000018266 mthfd1a / methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1a, methenyltetrahydrofolate cyclohydrolase, formyltetrahydrofolate synthetase / Q922D8* / MTHFD1* / P11586* / methylenet... / complex
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