ENSDARG00000018426


Danio rerio

Features
Gene ID: ENSDARG00000018426
  
Biological name :aldh7a1
  
Synonyms : aldehyde dehydrogenase 7 family, member A1 / aldh7a1
  
Possible biological names infered from orthology : Alpha-aminoadipic semialdehyde dehydrogenase / P49419 / Q9DBF1
  
Species: Danio rerio
  
Chr. number: 10
Strand: -1
Band:
Gene start: 16006905
Gene end: 16028082
  
Corresponding Affymetrix probe sets: Dr.2430.1.S1_at (Zebrafish Array)   NM_212724_at (Zebrafish Genome Array with custom cdf files)   
  
Cross references: Ensembl peptide - ENSDARP00000108190
NCBI entrez gene - 334197     See in Manteia.
RefSeq - NM_212724
RefSeq Peptide - NP_997889
swissprot - F1QR17
ZFIN ID - ZDB-GENE-030131-6129
Ensembl - ENSDARG00000018426
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ALDH7A1ENSGALG00000008229Gallus gallus
 P49419ENSG00000164904Homo sapiens
 Q9DBF1ENSMUSG00000053644Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
aldh2.2 / aldehyde dehydrogenase 2 family (mitochondrial), tandem duplicate 2 / ALDH2* / P05091* / AC002996.1* / aldehyde dehydrogenase 2 family (mitochondrial)*ENSDARG0000002808727
aldh1a2 / aldehyde dehydrogenase 1 family, member A2 / O94788* / Q62148* / Retinal dehydrogenase 2 *ENSDARG0000005349327
aldh1a3 / aldehyde dehydrogenase 1 family, member A3 / P47895* / Q9JHW9* / Aldehyde dehydrogenase family 1 member A3 *ENSDARG0000007693327
aldh2.1 / aldehyde dehydrogenase 2 family (mitochondrial), tandem duplicate 1 / ALDH2* / P05091* / AC002996.1* / aldehyde dehydrogenase 2 family (mitochondrial)*ENSDARG0000008992427
aldh1l2 / aldehyde dehydrogenase 1 family, member L2 / Q3SY69* / Q8K009* / Mitochondrial 10-formyltetrahydrofolate dehydrogenase *ENSDARG0000007023026
aldh1l1 / aldehyde dehydrogenase 1 family, member L1 / O75891*ENSDARG0000007700426
Q7ZVB2 / aldh9a1a.1 / aldehyde dehydrogenase 9 family, member A1a, tandem duplicate 1 / P49189* / ALDH9A1* / aldehyde dehydrogenase 9 family member A1*ENSDARG0000006910025
Q802W2 / aldh9a1b / aldehyde dehydrogenase 9 family, member A1b / P49189* / ALDH9A1* / aldehyde dehydrogenase 9 family member A1*ENSDARG0000003706124
aldh9a1a.2 / aldehyde dehydrogenase 9 family, member A1a, tandem duplicate 2 / P49189* / ALDH9A1* / aldehyde dehydrogenase 9 family member A1*ENSDARG0000005533123
Q66I21 / aldh8a1 / aldehyde dehydrogenase 8 family, member A1 / Q8BH00* / Q9H2A2* / Aldehyde dehydrogenase family 8 member A1 *ENSDARG0000003677622


Protein motifs (from Interpro)
Interpro ID Name
 IPR015590  Aldehyde dehydrogenase domain
 IPR016161  Aldehyde/histidinol dehydrogenase
 IPR016162  Aldehyde dehydrogenase, N-terminal
 IPR029510  Aldehyde dehydrogenase, glutamic acid active site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0008152 metabolic process IEA
 biological_processGO:0033339 pectoral fin development IMP
 biological_processGO:0043010 camera-type eye development IMP
 biological_processGO:0051216 cartilage development IMP
 biological_processGO:0055114 oxidation-reduction process IEA
 molecular_functionGO:0016491 oxidoreductase activity IEA
 molecular_functionGO:0016620 oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor IEA


Pathways (from Reactome)
Pathway description
Choline catabolism
Lysine catabolism


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000107 eye eye morphology , abnormal
eye perforate , abnormal
eye decreased size , abnormal
Show

 ZFA:0000152 retina retina cell proliferation disrupted , abnormal
Show

 ZFA:0000435 cranial nerve II cranial nerve II hypoplastic , abnormal
Show

 ZFA:0000445 optic tectum optic tectum electric potential , abnormal
optic tectum electric potential , ameliorated
Show

 ZFA:0001094 whole organism whole organism deformed , abnormal
whole organism life span , ameliorated
whole organism amount , ameliorated
whole organism increased amount , abnormal
whole organism increased behavioural activity , abnormal
whole organism dead , abnormal
whole organism decreased life span , abnormal
whole organism circling , abnormal
whole organism behavioural activity , ameliorated
whole organism taurine decreased amount , abnormal
whole organism methionine decreased amount , abnormal
whole organism gamma-aminobutyric acid decreased amount , abnormal
whole organism gamma-aminobutyric acid normal amount , ameliorated
whole organism L-saccharopine increased amount , abnormal
whole organism beta-alanine increased amount , abnormal
whole organism allysine increased amount , abnormal
whole organism pyridoxal decreased amount , abnormal
whole organism serine increased amount , abnormal
whole organism tyrosine increased amount , abnormal
whole organism pyridoxamine 5-phosphate decreased amount , abnormal
whole organism alpha-aminobutyric acid decreased amount , abnormal
whole organism pipecolate increased amount , abnormal
whole organism 1-piperideine-6-carboxylic acid increased amount , abnormal
Show

 ZFA:0001115 trunk trunk curved , abnormal
Show

 ZFA:0001117 post-vent region post-vent region bent , abnormal
Show

 ZFA:0001161 pectoral fin pectoral fin shortened , abnormal
Show

 ZFA:0001284 optic fissure optic fissure anatomical margin unfused from optic fissure anatomical margin, abnormal
Show

 ZFA:0001458 cranial cartilage cranial cartilage morphology , abnormal
Show

 ZFA:0001460 pharyngeal arch cartilage pharyngeal arch cartilage morphology , abnormal
Show

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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