ENSDARG00000070230


Danio rerio

Features
Gene ID: ENSDARG00000070230
  
Biological name :aldh1l2
  
Synonyms : aldehyde dehydrogenase 1 family, member L2 / aldh1l2
  
Possible biological names infered from orthology : Mitochondrial 10-formyltetrahydrofolate dehydrogenase / Q3SY69 / Q8K009
  
Species: Danio rerio
  
Chr. number: 4
Strand: 1
Band:
Gene start: 9028819
Gene end: 9048975
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSDARP00000093667
Ensembl peptide - ENSDARP00000127567
swissprot - E7EXW7
swissprot - X1WBH6
ZFIN ID - ZDB-GENE-100426-6
Ensembl - ENSDARG00000070230
  
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ALDH1L2ENSGALG00000012691Gallus gallus
 Q3SY69ENSG00000136010Homo sapiens
 Q8K009ENSMUSG00000020256Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
aldh1l1 / aldehyde dehydrogenase 1 family, member L1 / O75891*ENSDARG0000007700476
aldh1a2 / aldehyde dehydrogenase 1 family, member A2 / O94788* / Q62148* / Retinal dehydrogenase 2 *ENSDARG0000005349327
aldh2.1 / aldehyde dehydrogenase 2 family (mitochondrial), tandem duplicate 1 / ALDH2* / P05091* / AC002996.1* / aldehyde dehydrogenase 2 family (mitochondrial)*ENSDARG0000008992427
aldh2.2 / aldehyde dehydrogenase 2 family (mitochondrial), tandem duplicate 2 / ALDH2* / P05091* / AC002996.1* / aldehyde dehydrogenase 2 family (mitochondrial)*ENSDARG0000002808726
aldh1a3 / aldehyde dehydrogenase 1 family, member A3 / P47895* / Q9JHW9* / Aldehyde dehydrogenase family 1 member A3 *ENSDARG0000007693326
Q802W2 / aldh9a1b / aldehyde dehydrogenase 9 family, member A1b / P49189* / ALDH9A1* / aldehyde dehydrogenase 9 family member A1*ENSDARG0000003706121
Q66I21 / aldh8a1 / aldehyde dehydrogenase 8 family, member A1 / Q8BH00* / Q9H2A2* / Aldehyde dehydrogenase family 8 member A1 *ENSDARG0000003677620
Q7ZVB2 / aldh9a1a.1 / aldehyde dehydrogenase 9 family, member A1a, tandem duplicate 1 / P49189* / ALDH9A1* / aldehyde dehydrogenase 9 family member A1*ENSDARG0000006910020
aldh9a1a.2 / aldehyde dehydrogenase 9 family, member A1a, tandem duplicate 2 / P49189* / ALDH9A1* / aldehyde dehydrogenase 9 family member A1*ENSDARG0000005533119
aldh7a1 / aldehyde dehydrogenase 7 family, member A1 / P49419* / Q9DBF1* / Alpha-aminoadipic semialdehyde dehydrogenase *ENSDARG0000001842615


Protein motifs (from Interpro)
Interpro ID Name
 IPR001555  Phosphoribosylglycinamide formyltransferase, active site
 IPR002376  Formyl transferase, N-terminal
 IPR005793  Formyl transferase, C-terminal
 IPR009081  Phosphopantetheine binding ACP domain
 IPR011034  Formyl transferase-like, C-terminal domain superfamily
 IPR011407  10-formyltetrahydrofolate dehydrogenase
 IPR015590  Aldehyde dehydrogenase domain
 IPR016160  Aldehyde dehydrogenase, cysteine active site
 IPR016161  Aldehyde/histidinol dehydrogenase
 IPR016162  Aldehyde dehydrogenase, N-terminal
 IPR029510  Aldehyde dehydrogenase, glutamic acid active site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006730 one-carbon metabolic process IEA
 biological_processGO:0008152 metabolic process IEA
 biological_processGO:0009058 biosynthetic process IEA
 biological_processGO:0009258 10-formyltetrahydrofolate catabolic process IEA
 biological_processGO:0055114 oxidation-reduction process IEA
 cellular_componentGO:0005737 cytoplasm IEA
 molecular_functionGO:0003824 catalytic activity IEA
 molecular_functionGO:0004029 aldehyde dehydrogenase (NAD) activity IBA
 molecular_functionGO:0016155 formyltetrahydrofolate dehydrogenase activity IBA
 molecular_functionGO:0016491 oxidoreductase activity IEA
 molecular_functionGO:0016620 oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor IEA
 molecular_functionGO:0016742 hydroxymethyl-, formyl- and related transferase activity IEA


Pathways (from Reactome)
Pathway description
Metabolism of folate and pterines


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSDARG00000070230 aldh1l2 / aldehyde dehydrogenase 1 family, member L2 / Q3SY69* / Q8K009* / Mitochondrial 10-formyltetrahydrofolate dehydrogenase *  / complex






 

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