ENSDARG00000018907


Danio rerio

Features
Gene ID: ENSDARG00000018907
  
Biological name :kat6a
  
Synonyms : kat6a / K(lysine) acetyltransferase 6A
  
Possible biological names infered from orthology : lysine acetyltransferase 6A / Q92794
  
Species: Danio rerio
  
Chr. number: 5
Strand: -1
Band:
Gene start: 14394323
Gene end: 14443124
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSDARP00000014581
NCBI entrez gene - 266966     See in Manteia.
swissprot - A2CG09
ZFIN ID - ZDB-GENE-021022-3
Ensembl - ENSDARG00000018907
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 KAT6AENSGALG00000003641Gallus gallus
 KAT6AENSG00000083168Homo sapiens
 Kat6aENSMUSG00000031540Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
kat6b / K(lysine) acetyltransferase 6B / Q8BRB7* / Q8WYB5* / lysine acetyltransferase 6B* / Histone acetyltransferase KAT6B *ENSDARG0000005542926
kat7b / K(lysine) acetyltransferase 7b / KAT7* / O95251* / Q5SVQ0* / lysine acetyltransferase 7* / K(lysine) acetyltransferase 7*ENSDARG000000317709
kat5b / kat5a / K(lysine) acetyltransferase 5b / KAT5* / Q92993* / Q8CHK4* / lysine acetyltransferase 5* / Histone acetyltransferase KAT5 *ENSDARG000000045878
kat8 / K(lysine) acetyltransferase 8 / Q9D1P2* / Q9H7Z6* / lysine acetyltransferase 8* / Histone acetyltransferase KAT8 *ENSDARG000000271878
kat5b / K(lysine) acetyltransferase 5b / KAT5* / Q8CHK4* / Q92993* / lysine acetyltransferase 5* / Histone acetyltransferase KAT5 *ENSDARG000000459518


Protein motifs (from Interpro)
Interpro ID Name
 IPR001965  Zinc finger, PHD-type
 IPR002717  Histone acetyltransferase domain, MYST-type
 IPR005818  Linker histone H1/H5, domain H15
 IPR011011  Zinc finger, FYVE/PHD-type
 IPR011991  ArsR-like helix-turn-helix domain
 IPR013083  Zinc finger, RING/FYVE/PHD-type
 IPR016181  Acyl-CoA N-acyltransferase
 IPR019787  Zinc finger, PHD-finger
 IPR031280  Histone acetyltransferase KAT6A


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001502 cartilage condensation IMP
 biological_processGO:0006334 nucleosome assembly IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0009880 embryonic pattern specification IMP
 biological_processGO:0009952 anterior/posterior pattern specification IGI
 biological_processGO:0010172 embryonic body morphogenesis IMP
 biological_processGO:0014036 neural crest cell fate specification IMP
 biological_processGO:0016573 histone acetylation ISS
 biological_processGO:0043966 histone H3 acetylation IEA
 biological_processGO:0048513 animal organ development IEA
 biological_processGO:0048703 embryonic viscerocranium morphogenesis IMP
 biological_processGO:0048706 embryonic skeletal system development IMP
 biological_processGO:0051216 cartilage development IMP
 cellular_componentGO:0000786 nucleosome IEA
 cellular_componentGO:0000790 nuclear chromatin IDA
 cellular_componentGO:0005634 nucleus IC
 cellular_componentGO:0070776 MOZ/MORF histone acetyltransferase complex IEA
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0003713 transcription coactivator activity IEA
 molecular_functionGO:0004402 histone acetyltransferase activity IMP
 molecular_functionGO:0016740 transferase activity IEA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
HATs acetylate histones
Regulation of TP53 Activity through Acetylation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000095 pharyngeal arch 3-7 skeleton pharyngeal arch 3-7 skeleton quality , abnormal
Show

 ZFA:0001227 mandibular arch skeleton mandibular arch skeleton duplicated , abnormal
Show

 ZFA:0001276 pharyngeal arch 2 skeleton pharyngeal arch 2 skeleton aplastic , abnormal
Show

 ZFA:0001400 ceratohyal cartilage ceratohyal cartilage malformed , abnormal
Show

 ZFA:0001422 hyosymplectic cartilage hyosymplectic cartilage malformed , abnormal
Show

 ZFA:0001520 ceratobranchial 1 cartilage ceratobranchial 1 cartilage malformed , abnormal
Show

 ZFA:0001611 pharyngeal arch 2 pharyngeal arch 2 physical object quality , abnormal
pharyngeal arch 2 joint absent , abnormal
Show

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSDARG00000035559 tp53 / P79734 / tumor protein p53 / Trp53* / P04637* / P02340* / transformation related protein 53*  / complex
 ENSDARG00000022413 ing5a / inhibitor of growth family, member 5a / ING5* / Q8WYH8* / Q9D8Y8* / Inhibitor of growth protein 5 * / inhibitor of growth family member 5*  / complex
 ENSDARG00000101216 meaf6 / Q6AZD3 / MYST/Esa1-associated factor 6 / Q2VPQ9* / Q9HAF1*  / complex
 ENSDARG00000017929 ncoa2 / nuclear receptor coactivator 2 / Q15596* / Q61026*  / complex / reaction






 

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