Manteia

ENSDARG00000017929

Danio rerio

Features

Gene ID:	ENSDARG00000017929

Biological name :	ncoa2

Synonyms :	ncoa2 / nuclear receptor coactivator 2

Possible biological names infered from orthology :	Q15596 / Q61026

Species:	Danio rerio

Chr. number:	24
Strand:	1
Band:
Gene start:	14240196
Gene end:	14445137

Corresponding Affymetrix probe sets:	Dr.11723.1.S1_at (Zebrafish Array)

Cross references:	Ensembl peptide - ENSDARP00000109306 Ensembl peptide - ENSDARP00000157542 Ensembl peptide - ENSDARP00000107210 NCBI entrez gene - 81884 See in Manteia. RefSeq - XM_009297336 RefSeq - XM_021470228 swissprot - E7F5J8 swissprot - F6NH98 ZFIN ID - ZDB-GENE-010406-3 Ensembl - ENSDARG00000017929

See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed

Ortholog prediction (from Ensembl)

Paralog prediction (from Ensembl)

Paralog name	ID	Similarity(%)
ncoa3 / nuclear receptor coactivator 3 / Q9Y6Q9*	ENSDARG00000077404	37
ncoa1 / nuclear receptor coactivator 1 / P70365* / Q15788*	ENSDARG00000018257	30

Protein motifs (from Interpro)

Interpro ID	Name
IPR000014	PAS domain
IPR009110	Nuclear receptor coactivator, interlocking
IPR010011	Domain of unknown function DUF1518
IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
IPR013767	PAS fold
IPR014920	Nuclear receptor coactivator, Ncoa-type, interlocking
IPR014935	Nuclear receptor coactivator, receptor-binding domain
IPR017426	Nuclear receptor coactivator
IPR028822	Nuclear receptor coactivator 2
IPR032565	Domain of unknown function DUF4927

Gene Ontology (GO)

Type	GO ID	Term	Ev.Code
biological_process	GO:0006351	transcription, DNA-templated	IEA
biological_process	GO:0006355	regulation of transcription, DNA-templated	IEA
cellular_component	GO:0005634	nucleus	IEA
molecular_function	GO:0003713	transcription coactivator activity	IEA
molecular_function	GO:0030374	nuclear receptor transcription coactivator activity	IEA
molecular_function	GO:0035257	nuclear hormone receptor binding	IEA
molecular_function	GO:0046983	protein dimerization activity	IEA

Pathways (from Reactome)

Pathway description

Recycling of bile acids and salts

Phenotype (from MGI, Zfin or HPO)

ID	Phenotype	Definition	Genetic BG
ZFA:0000033	intermediate cell mass of mesoderm	intermediate cell mass of mesoderm aplastic , abnormal	Show
ZFA:0000135	notochord	notochord deformed , abnormal	Show
ZFA:0000155	somite	somite U-shaped , abnormal	Show
ZFA:0001117	post-vent region	post-vent region decreased length , abnormal	Show
ZFA:0001285	intersegmental vessel	intersegmental vessel aplastic , abnormal	Show

Interacting proteins (from Reactome)

Interactor ID	Name	Interaction type
ENSDARG00000018257	ncoa1 / nuclear receptor coactivator 1 / P70365* / Q15788*	/ complex / reaction
ENSDARG00000067976	ar / androgen receptor / P10275* / P19091*	/ complex / reaction
ENSDARG00000018907	kat6a / K(lysine) acetyltransferase 6A / Q92794* / lysine acetyltransferase 6A*	/ complex / reaction
ENSDARG00000057737	rxraa / retinoid X receptor, alpha a / RXRA* / P19793* / P28700* / retinoid X receptor alpha*	/ complex / reaction

0 s.

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		© Olivier Tassy / Olivier Pourquie 2007-2025 contact: otassy@igbmc.fr