ENSDARG00000018976


Danio rerio

Features
Gene ID: ENSDARG00000018976
  
Biological name :sptlc2a
  
Synonyms : serine palmitoyltransferase, long chain base subunit 2a / sptlc2a
  
Possible biological names infered from orthology : O15270 / P97363 / serine palmitoyltransferase long chain base subunit 2 / SPTLC2
  
Species: Danio rerio
  
Chr. number: 17
Strand: 1
Band:
Gene start: 17804727
Gene end: 17856118
  
Corresponding Affymetrix probe sets: Dr.16885.1.A1_at (Zebrafish Array)   NM_001020619_at (Zebrafish Genome Array with custom cdf files)   
  
Cross references: Ensembl peptide - ENSDARP00000123952
Ensembl peptide - ENSDARP00000109825
NCBI entrez gene - 553646     See in Manteia.
RefSeq - NM_001020619
RefSeq Peptide - NP_001018455
swissprot - F8W491
swissprot - F1QCX4
ZFIN ID - ZDB-GENE-050522-23
Ensembl - ENSDARG00000018976
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 SPTLC2ENSGALG00000031928Gallus gallus
 O15270ENSG00000100596Homo sapiens
 P97363ENSMUSG00000021036Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
sptlc2b / serine palmitoyltransferase, long chain base subunit 2b / O15270* / SPTLC2* / serine palmitoyltransferase long chain base subunit 2*ENSDARG0000007428778
sptlc3 / serine palmitoyltransferase, long chain base subunit 3 / Q8BG54* / Q9NUV7* / Mus musculus serine palmitoyltransferase, long chain base subunit 3 (Sptlc3), transcript variant 1, mRNA.*ENSDARG0000003074365


Protein motifs (from Interpro)
Interpro ID Name
 IPR001917  Aminotransferase, class-II, pyridoxal-phosphate binding site
 IPR004839  Aminotransferase, class I/classII
 IPR015421  Pyridoxal phosphate-dependent transferase, major domain
 IPR015422  Pyridoxal phosphate-dependent transferase domain 1
 IPR015424  Pyridoxal phosphate-dependent transferase


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0008152 metabolic process IEA
 biological_processGO:0009058 biosynthetic process IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0003824 catalytic activity IEA
 molecular_functionGO:0016740 transferase activity IEA
 molecular_functionGO:0030170 pyridoxal phosphate binding IEA


Pathways (from Reactome)
Pathway description
Sphingolipid de novo biosynthesis


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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