ENSDARG00000030743


Danio rerio

Features
Gene ID: ENSDARG00000030743
  
Biological name :sptlc3
  
Synonyms : serine palmitoyltransferase, long chain base subunit 3 / sptlc3
  
Possible biological names infered from orthology : Mus musculus serine palmitoyltransferase, long chain base subunit 3 (Sptlc3), transcript variant 1, mRNA. / Q8BG54 / Q9NUV7
  
Species: Danio rerio
  
Chr. number: 13
Strand: -1
Band:
Gene start: 34804243
Gene end: 34862484
  
Corresponding Affymetrix probe sets: Dr.20265.1.S1_at (Zebrafish Array)   NM_001003562_at (Zebrafish Genome Array with custom cdf files)   
  
Cross references: Ensembl peptide - ENSDARP00000047551
Ensembl peptide - ENSDARP00000116719
Ensembl peptide - ENSDARP00000146370
NCBI entrez gene - 445168     See in Manteia.
RefSeq - NM_001003562
RefSeq - XM_021480564
RefSeq Peptide - NP_001003562
swissprot - Q5RG23
swissprot - F1QQP7
ZFIN ID - ZDB-GENE-041210-281
Ensembl - ENSDARG00000030743
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 SPTLC3ENSGALG00000009037Gallus gallus
 Q9NUV7ENSG00000172296Homo sapiens
 Q8BG54ENSMUSG00000039092Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
sptlc2a / serine palmitoyltransferase, long chain base subunit 2a / O15270* / P97363* / SPTLC2* / serine palmitoyltransferase long chain base subunit 2*ENSDARG0000001897666
sptlc2b / serine palmitoyltransferase, long chain base subunit 2b / O15270* / SPTLC2* / serine palmitoyltransferase long chain base subunit 2*ENSDARG0000007428766


Protein motifs (from Interpro)
Interpro ID Name
 IPR004839  Aminotransferase, class I/classII
 IPR015421  Pyridoxal phosphate-dependent transferase, major domain
 IPR015422  Pyridoxal phosphate-dependent transferase domain 1
 IPR015424  Pyridoxal phosphate-dependent transferase


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0009058 biosynthetic process IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0003824 catalytic activity IEA
 molecular_functionGO:0030170 pyridoxal phosphate binding IEA


Pathways (from Reactome)
Pathway description
Sphingolipid de novo biosynthesis


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0009052 motor neuron motor neuron axon guidance process quality , abnormal
motor neuron axon morphology , abnormal
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Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSDARG00000042995 sptlc1 / serine palmitoyltransferase, long chain base subunit 1 / O15269* / O35704* / Serine palmitoyltransferase 1 *  / complex
 ENSDARG00000071203 Q5BJC1 / sptssa / serine palmitoyltransferase, small subunit A / Q8R207* / Gm6993* / Q969W0*  / complex
 ENSDARG00000091658 Q1RLT2 / sptssb / serine palmitoyltransferase, small subunit B / Q8NFR3* / Q925E8*  / complex






 

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