ENSDARG00000019008


Danio rerio

Features
Gene ID: ENSDARG00000019008
  
Biological name :erp44
  
Synonyms : endoplasmic reticulum protein 44 / erp44
  
Possible biological names infered from orthology : Endoplasmic reticulum resident protein 44 / Q9BS26 / Q9D1Q6
  
Species: Danio rerio
  
Chr. number: 16
Strand: -1
Band:
Gene start: 27417200
Gene end: 27442344
  
Corresponding Affymetrix probe sets: Dr.2478.1.S1_at (Zebrafish Array)   NM_200892_at (Zebrafish Genome Array with custom cdf files)   
  
Cross references: Ensembl peptide - ENSDARP00000017258
NCBI entrez gene - 393866     See in Manteia.
RefSeq - NM_200892
RefSeq Peptide - NP_957186
swissprot - Q6P3G9
ZFIN ID - ZDB-GENE-040426-1902
Ensembl - ENSDARG00000019008
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ERP44ENSGALG00000013452Gallus gallus
 ERP44ENSG00000023318Homo sapiens
 Erp44ENSMUSG00000028343Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
pdia4 / protein disulfide isomerase family A, member 4 / P13667*ENSDARG0000001849123
zgc:77086ENSDARG0000001401521
pdia2 / protein disulfide isomerase family A, member 2 / D3Z6P0* / Q13087* / Protein disulfide-isomerase A2 *ENSDARG0000001826321
p4hb / prolyl 4-hydroxylase, beta polypeptide / P07237* / P09103* / prolyl 4-hydroxylase subunit beta*ENSDARG0000010511621
zgc:100906ENSDARG0000003359919
pdia3 / protein disulfide isomerase family A, member 3 / P27773* / P30101* / Protein disulfide-isomerase A3 *ENSDARG0000010264019
zgc:136472 / PDILT* / Q9DAN1* / Q8N807* / protein disulfide isomerase like, testis expressed* / Protein disulfide-isomerase-like protein of the testis *ENSDARG0000005844517
tmx3a / thioredoxin related transmembrane protein 3a / TMX3* / Q8BXZ1* / Q96JJ7* / Protein disulfide-isomerase TMX3 * / thioredoxin related transmembrane protein 3*ENSDARG0000003889414
tmx3b / thioredoxin related transmembrane protein 3b / TMX3* / Q96JJ7* / thioredoxin related transmembrane protein 3*ENSDARG000000884666


Protein motifs (from Interpro)
Interpro ID Name
 IPR012336  Thioredoxin-like fold
 IPR013766  Thioredoxin domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006457 protein folding IBA
 biological_processGO:0007507 heart development IMP
 biological_processGO:0010882 regulation of cardiac muscle contraction by calcium ion signaling IMP
 biological_processGO:0034976 response to endoplasmic reticulum stress IBA
 biological_processGO:0045454 cell redox homeostasis IEA
 cellular_componentGO:0005783 endoplasmic reticulum IBA
 molecular_functionGO:0003756 protein disulfide isomerase activity IBA


Pathways (from Reactome)
Pathway description
Neutrophil degranulation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000009 cardiac ventricle cardiac ventricle morphology , abnormal
Show

 ZFA:0000054 pericardium pericardium edematous , abnormal
Show

 ZFA:0000114 heart heart increased size , abnormal
heart calcium-mediated signaling disrupted , abnormal
Show

 ZFA:0000471 atrium atrium morphology , abnormal
atrium increased size , abnormal
Show

 ZFA:0001094 whole organism whole organism dead , abnormal
Show

 ZFA:0001115 trunk trunk curved , abnormal
Show

 ZFA:0001317 endocardial cushion endocardial cushion lacks parts or has fewer parts of type cardiac muscle cell , abnormal
Show

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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