ENSDARG00000020053


Danio rerio

Features
Gene ID: ENSDARG00000020053
  
Biological name :nkd1
  
Synonyms : naked cuticle homolog 1 (Drosophila) / nkd1 / Q2TJA6
  
Possible biological names infered from orthology : naked cuticle homolog 1 / Protein naked cuticle homolog 1 / Q969G9 / Q99MH6
  
Species: Danio rerio
  
Chr. number: 7
Strand: -1
Band:
Gene start: 37582281
Gene end: 37622370
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSDARP00000052378
Ensembl peptide - ENSDARP00000142757
NCBI entrez gene - 751108     See in Manteia.
RefSeq - XM_005169004
RefSeq Peptide - NP_001036798
swissprot - B0S7E2
swissprot - A0A1I7Q3W8
swissprot - Q2TJA6
ZFIN ID - ZDB-GENE-061108-3
Ensembl - ENSDARG00000020053
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 NKD1ENSGALG00000003767Gallus gallus
 NKD1ENSG00000140807Homo sapiens
 Nkd1ENSMUSG00000031661Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
nkd2a / naked cuticle homolog 2a / NKD2* / Q8VE28* / Q969F2* / naked cuticle homolog 2* / Mus musculus naked cuticle 2 (Nkd2), transcript variant 2, mRNA.*ENSDARG0000005527135
nkd3 / naked cuticle homolog 3 / NKD2* / Q8VE28* / Q969F2* / naked cuticle homolog 2* / Mus musculus naked cuticle 2 (Nkd2), transcript variant 2, mRNA.*ENSDARG0000001317430


Protein motifs (from Interpro)
Interpro ID Name
 IPR002048  EF-hand domain
 IPR011992  EF-hand domain pair
 IPR018247  EF-Hand 1, calcium-binding site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001754 eye photoreceptor cell differentiation IEA
 biological_processGO:0001839 neural plate morphogenesis IGI
 biological_processGO:0003146 heart jogging IMP
 biological_processGO:0007525 somatic muscle development IEA
 biological_processGO:0016055 Wnt signaling pathway IMP
 biological_processGO:0042308 negative regulation of protein import into nucleus IDA
 biological_processGO:0060061 Spemann organizer formation IMP
 biological_processGO:0060828 regulation of canonical Wnt signaling pathway IEA
 biological_processGO:0060971 embryonic heart tube left/right pattern formation IMP
 biological_processGO:0060972 left/right pattern formation IMP
 biological_processGO:0070121 Kupffer"s vesicle development IMP
 biological_processGO:0090090 negative regulation of canonical Wnt signaling pathway IEA
 biological_processGO:0090249 regulation of cell motility involved in somitogenic axis elongation IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005886 plasma membrane IDA
 cellular_componentGO:0016020 membrane IEA
 molecular_functionGO:0005509 calcium ion binding IEA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000001 Kupffer s vesicle Kupffers vesicle decreased size , abnormal
Kupffers vesicle cilium decreased amount , abnormal
Kupffers vesicle aplastic , abnormal
Show

 ZFA:0000028 heart primordium heart primordium bifurcated , abnormal
Show

 ZFA:0000360 heart tube heart tube bifurcated , abnormal
Show

 ZFA:0001125 organizer inducing center organizer inducing center increased width , abnormal
Show

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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