ENSG00000140807


Homo sapiens

Features
Gene ID: ENSG00000140807
  
Biological name :NKD1
  
Synonyms : naked cuticle homolog 1 / NKD1 / Q969G9
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 16
Strand: 1
Band: q12.1
Gene start: 50548330
Gene end: 50649249
  
Corresponding Affymetrix probe sets: 1553115_at (Human Genome U133 Plus 2.0 Array)   229481_at (Human Genome U133 Plus 2.0 Array)   229613_at (Human Genome U133 Plus 2.0 Array)   232203_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000268459
NCBI entrez gene - 85407     See in Manteia.
OMIM - 607851
RefSeq - XM_017023804
RefSeq - NM_033119
RefSeq - XM_011523399
RefSeq - XM_011523400
RefSeq Peptide - NP_149110
swissprot - Q969G9
Ensembl - ENSG00000140807
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 nkd1ENSDARG00000020053Danio rerio
 NKD1ENSGALG00000003767Gallus gallus
 Nkd1ENSMUSG00000031661Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
NKD2 / Q969F2 / naked cuticle homolog 2ENSG0000014550641


Protein motifs (from Interpro)
Interpro ID Name
 IPR002048  EF-hand domain
 IPR011992  EF-hand domain pair
 IPR018247  EF-Hand 1, calcium-binding site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001754 eye photoreceptor cell differentiation ISS
 biological_processGO:0007525 somatic muscle development ISS
 biological_processGO:0016055 Wnt signaling pathway IEA
 biological_processGO:0030178 negative regulation of Wnt signaling pathway IEA
 biological_processGO:0045732 positive regulation of protein catabolic process IMP
 biological_processGO:0090090 negative regulation of canonical Wnt signaling pathway IEA
 biological_processGO:0090249 regulation of cell motility involved in somitogenic axis elongation ISS
 biological_processGO:1901231 positive regulation of non-canonical Wnt signaling pathway via JNK cascade IEA
 biological_processGO:1901233 negative regulation of convergent extension involved in axis elongation IEA
 biological_processGO:2000096 positive regulation of Wnt signaling pathway, planar cell polarity pathway IEA
 cellular_componentGO:0000159 protein phosphatase type 2A complex IDA
 cellular_componentGO:0005737 cytoplasm IBA
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0016020 membrane IEA
 molecular_functionGO:0005509 calcium ion binding IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0030165 PDZ domain binding IEA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

0 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2025
contact: otassy@igbmc.fr