ENSG00000145506


Homo sapiens

Features
Gene ID: ENSG00000145506
  
Biological name :NKD2
  
Synonyms : naked cuticle homolog 2 / NKD2 / Q969F2
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 5
Strand: 1
Band: p15.33
Gene start: 1008829
Gene end: 1038943
  
Corresponding Affymetrix probe sets: 232201_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000274150
Ensembl peptide - ENSP00000296849
NCBI entrez gene - 85409     See in Manteia.
OMIM - 607852
RefSeq - XM_011514150
RefSeq - NM_001271082
RefSeq - NM_033120
RefSeq - XM_005248382
RefSeq - XM_005248383
RefSeq Peptide - NP_001258011
RefSeq Peptide - NP_149111
swissprot - Q969F2
Ensembl - ENSG00000145506
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 nkd2aENSDARG00000055271Danio rerio
 nkd3ENSDARG00000013174Danio rerio
 Nkd2ENSMUSG00000021567Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
NKD1 / Q969G9 / naked cuticle homolog 1ENSG0000014080743


Protein motifs (from Interpro)
Interpro ID Name
 IPR002048  EF-hand domain
 IPR011992  EF-hand domain pair


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006887 exocytosis IEA
 biological_processGO:0010954 positive regulation of protein processing IDA
 biological_processGO:0016055 Wnt signaling pathway IEA
 biological_processGO:0032436 positive regulation of proteasomal ubiquitin-dependent protein catabolic process IMP
 biological_processGO:0048210 Golgi vesicle fusion to target membrane IMP
 biological_processGO:0072659 protein localization to plasma membrane IMP
 biological_processGO:0090090 negative regulation of canonical Wnt signaling pathway IMP
 biological_processGO:1903078 positive regulation of protein localization to plasma membrane IDA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005886 plasma membrane IDA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016323 basolateral plasma membrane IDA
 cellular_componentGO:0016328 lateral plasma membrane IDA
 cellular_componentGO:0031410 cytoplasmic vesicle IDA
 cellular_componentGO:0070382 exocytic vesicle IDA
 cellular_componentGO:0071944 cell periphery IDA
 molecular_functionGO:0005509 calcium ion binding IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0019838 growth factor binding IPI
 molecular_functionGO:0031625 ubiquitin protein ligase binding IPI
 molecular_functionGO:0032036 myosin heavy chain binding IPI
 molecular_functionGO:0046872 metal ion binding IEA
 molecular_functionGO:0051117 ATPase binding IPI


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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