ENSDARG00000020574


Danio rerio

Features
Gene ID: ENSDARG00000020574
  
Biological name :atp2a1
  
Synonyms : atp2a1 / ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 1
  
Possible biological names infered from orthology :
  
Species: Danio rerio
  
Chr. number: 3
Strand: 1
Band:
Gene start: 26081343
Gene end: 26157066
  
Corresponding Affymetrix probe sets: Dr.20010.7.S1_at (Zebrafish Array)   NM_001007029_at (Zebrafish Genome Array with custom cdf files)   
  
Cross references: Ensembl peptide - ENSDARP00000115435
Ensembl peptide - ENSDARP00000135633
Ensembl peptide - ENSDARP00000116872
Ensembl peptide - ENSDARP00000116177
Ensembl peptide - ENSDARP00000043931
Ensembl peptide - ENSDARP00000109874
NCBI entrez gene - 260440     See in Manteia.
RefSeq - NM_001007029
RefSeq Peptide - NP_001007030
swissprot - E9QCD9
swissprot - Q5U3A4
swissprot - Q642Z0
swissprot - E9QGF0
swissprot - E9QF60
ZFIN ID - ZDB-GENE-020905-1
Ensembl - ENSDARG00000020574
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
No match


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
atp2a1l / ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 1, likeENSDARG0000003545888
atp2a2a / ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 2a / ATP2A2* / O55143* / P16615* / Sarcoplasmic/endoplasmic reticulum calcium ATPase 2 * / ATPase sarcoplasmic/endoplas...ENSDARG0000002943983
atp2a2a / atp2a2b / ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 2a / ATP2A2* / O55143* / P16615* / Sarcoplasmic/endoplasmic reticulum calcium ATPase 2 * / ATPase sarcoplasmi...ENSDARG0000000512280
atp2a3 / ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 3 / Q64518* / Q93084* / Sarcoplasmic/endoplasmic reticulum calcium ATPase 3 *ENSDARG0000006097880
si:dkey-28b4.8ENSDARG0000000284076
atp2c1 / ATPase secretory pathway Ca2+ transporting 1 / P98194* / Q80XR2* / Calcium-transporting ATPase type 2C member 1 *ENSDARG0000006019731
atp1a1a.4 / ATPase Na+/K+ transporting subunit alpha 1a, tandem duplicate 4 / ATP1A1* / P05023* / Q8VDN2* / ATPase Na+/K+ transporting subunit alpha 1* / Sodium/potassium-transporting ATPas...ENSDARG0000000187028
atp1a1a.1 / ATPase Na+/K+ transporting subunit alpha 1a, tandem duplicate 1 / ATP1A1* / P05023* / Q8VDN2* / ATPase Na+/K+ transporting subunit alpha 1* / Sodium/potassium-transporting ATPas...ENSDARG0000000279128
atp1a1a.2 / ATPase Na+/K+ transporting subunit alpha 1a, tandem duplicate 2 / ATP1A1* / P05023* / Q8VDN2* / ATPase Na+/K+ transporting subunit alpha 1* / Sodium/potassium-transporting ATPas...ENSDARG0000000773928
atp1a2a / ATPase Na+/K+ transporting subunit alpha 2 / ATP1A2* / P50993* / Q6PIE5* / Sodium/potassium-transporting ATPase subunit alpha-2 *ENSDARG0000001047228
atp1a3a / ATPase Na+/K+ transporting subunit alpha 3a / P13637* / ATP1A3* / Q6PIC6* / AC010616.2* / ATPase Na+/K+ transporting subunit alpha 3* / Sodium/potassium-transporting ATPase subuni...ENSDARG0000001825928
atp1a1b / ATPase Na+/K+ transporting subunit alpha 1b / ATP1A1* / P05023* / Q8VDN2* / ATPase Na+/K+ transporting subunit alpha 1* / Sodium/potassium-transporting ATPase subunit alpha-1 *ENSDARG0000001985628
atp1a1a.5 / ATPase Na+/K+ transporting subunit alpha 1a, tandem duplicate 5 / ATP1A1* / P05023* / Q8VDN2* / ATPase Na+/K+ transporting subunit alpha 1* / Sodium/potassium-transporting ATPas...ENSDARG0000004025228
atp1a3b / ATPase Na+/K+ transporting subunit alpha 3b / P13637* / ATP1A3* / Q6PIC6* / AC010616.2* / ATPase Na+/K+ transporting subunit alpha 3* / Sodium/potassium-transporting ATPase subuni...ENSDARG0000010413928
atp1a1a.3 / ATPase Na+/K+ transporting subunit alpha 1a, tandem duplicate 3 / ATP1A1* / P05023* / Q8VDN2* / ATPase Na+/K+ transporting subunit alpha 1* / Sodium/potassium-transporting ATPas...ENSDARG0000003913127


Protein motifs (from Interpro)
Interpro ID Name
 IPR001757  P-type ATPase
 IPR004014  Cation-transporting P-type ATPase, N-terminal
 IPR005782  P-type ATPase, subfamily IIA, SERCA-type
 IPR006068  Cation-transporting P-type ATPase, C-terminal
 IPR008250  P-type ATPase, A domain superfamily
 IPR018303  P-type ATPase, phosphorylation site
 IPR023214  HAD superfamily
 IPR023298  P-type ATPase, transmembrane domain superfamily
 IPR023299  P-type ATPase, cytoplasmic domain N


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006811 ion transport IEA
 biological_processGO:0006816 calcium ion transport IEA
 biological_processGO:0006874 cellular calcium ion homeostasis IMP
 biological_processGO:0006937 regulation of muscle contraction IMP
 biological_processGO:0006942 regulation of striated muscle contraction ISS
 biological_processGO:0009612 response to mechanical stimulus IMP
 biological_processGO:0031448 positive regulation of fast-twitch skeletal muscle fiber contraction ISS
 biological_processGO:0045932 negative regulation of muscle contraction IMP
 biological_processGO:0045988 negative regulation of striated muscle contraction ISS
 biological_processGO:0070588 calcium ion transmembrane transport IEA
 biological_processGO:0090076 relaxation of skeletal muscle IMP
 biological_processGO:0099132 ATP hydrolysis coupled cation transmembrane transport IEA
 cellular_componentGO:0005623 cell IEA
 cellular_componentGO:0005783 endoplasmic reticulum ISS
 cellular_componentGO:0005789 endoplasmic reticulum membrane ISS
 cellular_componentGO:0005793 endoplasmic reticulum-Golgi intermediate compartment ISS
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0016529 sarcoplasmic reticulum ISS
 cellular_componentGO:0031673 H zone ISS
 cellular_componentGO:0031674 I band ISS
 cellular_componentGO:0048471 perinuclear region of cytoplasm ISS
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0005388 calcium-transporting ATPase activity IEA
 molecular_functionGO:0005509 calcium ion binding ISS
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0016787 hydrolase activity IEA
 molecular_functionGO:0016887 ATPase activity ISS


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000135 notochord notochord degenerate , abnormal
notochord damaged , abnormal
notochord condensed , abnormal
notochord damaged , ameliorated
Show

 ZFA:0000473 trunk musculature trunk musculature quality , abnormal
trunk musculature contractility , abnormal
Show

 ZFA:0001094 whole organism whole organism shape , abnormal
whole organism bent , abnormal
whole organism lethal (sensu genetics) , abnormal
whole organism viability , abnormal
whole organism movement behavioral quality , abnormal
Show

 ZFA:0001115 trunk trunk bent , abnormal
trunk bent , ameliorated
Show

 ZFA:0009117 fast muscle cell fast muscle cell skeletal muscle myofibril disorganized , abnormal
fast muscle cell skeletal muscle myofibril disorganized , ameliorated
Show

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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