ENSDARG00000021154


Danio rerio

Features
Gene ID: ENSDARG00000021154
  
Biological name :zgc:92040
  
Synonyms : zgc:92040
  
Possible biological names infered from orthology : PRODH2 / proline dehydrogenase 2 / proline dehydrogenase (oxidase) 2 / Q8VCZ9 / Q9UF12
  
Species: Danio rerio
  
Chr. number: 12
Strand: -1
Band:
Gene start: 3926168
Gene end: 3940768
  
Corresponding Affymetrix probe sets: Dr.4851.1.A1_at (Zebrafish Array)   
  
Cross references: Ensembl peptide - ENSDARP00000118592
NCBI entrez gene - 436664     See in Manteia.
swissprot - F1QCH4
ZFIN ID - ZDB-GENE-040718-87
Ensembl - ENSDARG00000021154
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 PRODH2ENSG00000250799Homo sapiens
 Prodh2ENSMUSG00000036892Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
prodha / proline dehydrogenase (oxidase) 1a / PRODH* / Q9WU79* / O43272* / proline dehydrogenase 1* / Proline dehydrogenase 1, mitochondrial *ENSDARG0000008674633
prodhb / proline dehydrogenase (oxidase) 1b / PRODH* / O43272* / proline dehydrogenase 1*ENSDARG0000008651225


Protein motifs (from Interpro)
Interpro ID Name
 IPR002872  Proline dehydrogenase domain
 IPR015659  Proline oxidase family
 IPR029041  FAD-linked oxidoreductase-like


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006560 proline metabolic process IEA
 biological_processGO:0006562 proline catabolic process IEA
 biological_processGO:0010133 proline catabolic process to glutamate IBA
 biological_processGO:0055114 oxidation-reduction process IEA
 cellular_componentGO:0005739 mitochondrion IBA
 molecular_functionGO:0004657 proline dehydrogenase activity IBA
 molecular_functionGO:0016491 oxidoreductase activity IEA
 molecular_functionGO:0071949 FAD binding IBA


Pathways (from Reactome)
Pathway description
Glyoxylate metabolism and glycine degradation
Proline catabolism


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSDARG00000021154 zgc:92040 / PRODH2* / Q8VCZ9* / Q9UF12* / proline dehydrogenase 2* / proline dehydrogenase (oxidase) 2*  / complex






 

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contact: otassy@igbmc.fr