ENSDARG00000021996


Danio rerio

Features
Gene ID: ENSDARG00000021996
  
Biological name :ppp2r2aa
  
Synonyms : ppp2r2aa / protein phosphatase 2, regulatory subunit B, alpha a
  
Possible biological names infered from orthology : P63151 / PPP2R2A / protein phosphatase 2, regulatory subunit B, alpha / protein phosphatase 2 regulatory subunit Balpha / Q6P1F6
  
Species: Danio rerio
  
Chr. number: 8
Strand: -1
Band:
Gene start: 5233450
Gene end: 5267442
  
Corresponding Affymetrix probe sets: Dr.11500.1.S1_at (Zebrafish Array)   
  
Cross references: Ensembl peptide - ENSDARP00000128373
NCBI entrez gene - 558752     See in Manteia.
swissprot - X1WDS4
ZFIN ID - ZDB-GENE-130530-565
Ensembl - ENSDARG00000021996
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 PPP2R2AENSGALG00000000235Gallus gallus
 P63151ENSG00000221914Homo sapiens
 Q6P1F6ENSMUSG00000022052Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
ppp2r2ab / protein phosphatase 2, regulatory subunit B, alpha b / Q6P1F6* / P63151* / PPP2R2A* / protein phosphatase 2 regulatory subunit Balpha* / protein phosphatase 2, regulatory subunit B, alpha*ENSDARG0000000662483
Q6NY64 / ppp2r2d / protein phosphatase 2, regulatory subunit B, delta / Q66LE6* / protein phosphatase 2 regulatory subunit Bdelta*ENSDARG0000010200978
ppp2r2bb / protein phosphatase 2, regulatory subunit B, beta b / Q6ZWR4* / Q00005* / PPP2R2B* / protein phosphatase 2 regulatory subunit Bbeta* / protein phosphatase 2, regulatory subunit B, beta*ENSDARG0000009922174
ppp2r2ba / ppp2r2ca / protein phosphatase 2, regulatory subunit B, beta a / Q6ZWR4* / Q00005* / PPP2R2B* / protein phosphatase 2 regulatory subunit Bbeta* / protein phosphatase 2, regulator...ENSDARG0000010009372
ppp2r2ca / protein phosphatase 2, regulatory subunit B, gamma a / Q9Y2T4* / PPP2R2C* / protein phosphatase 2 regulatory subunit Bgamma*ENSDARG0000005679769
ppp2r2cb / protein phosphatase 2, regulatory subunit B, gamma b / Q9Y2T4* / Q8BG02* / PPP2R2C* / protein phosphatase 2 regulatory subunit Bgamma* / protein phosphatase 2, regulatory subunit B, gamma*ENSDARG0000006227766


Protein motifs (from Interpro)
Interpro ID Name
 IPR000009  Protein phosphatase 2A regulatory subunit PR55
 IPR001680  WD40 repeat
 IPR015943  WD40/YVTN repeat-like-containing domain superfamily
 IPR017986  WD40-repeat-containing domain
 IPR018067  Protein phosphatase 2A regulatory subunit PR55, conserved site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0043666 regulation of phosphoprotein phosphatase activity IEA
 biological_processGO:0072554 blood vessel lumenization IGI
 cellular_componentGO:0000159 protein phosphatase type 2A complex IEA
 molecular_functionGO:0019888 protein phosphatase regulator activity IEA


Pathways (from Reactome)
Pathway description
Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0001285 intersegmental vessel intersegmental vessel decreased thickness , abnormal
intersegmental vessel blood vessel lumenization process quality , abnormal
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 ZFA:0005025 dorsal longitudinal anastomotic vessel dorsal longitudinal anastomotic vessel decreased thickness , abnormal
dorsal longitudinal anastomotic vessel blood vessel lumenization process quality , abnormal
Show

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSDARG00000053404 PPP2CA / zgc:56064 / P67775* / P63330* / protein phosphatase 2 catalytic subunit alpha* / Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform *  / complex






 

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