ENSDARG00000022767


Danio rerio

Features
Gene ID: ENSDARG00000022767
  
Biological name :apobb.1
  
Synonyms : apobb.1 / apolipoprotein Bb, tandem duplicate 1
  
Possible biological names infered from orthology : APOB / apolipoprotein B / Apolipoprotein B-100 Apolipoprotein B-48 / E9Q414 / P04114
  
Species: Danio rerio
  
Chr. number: 20
Strand: 1
Band:
Gene start: 31269778
Gene end: 31285980
  
Corresponding Affymetrix probe sets: Dr.5562.1.S1_at (Zebrafish Array)   NM_001030062_at (Zebrafish Genome Array with custom cdf files)   
  
Cross references: Ensembl peptide - ENSDARP00000144163
Ensembl peptide - ENSDARP00000119179
NCBI entrez gene - 321166     See in Manteia.
RefSeq - NM_001030062
RefSeq - XM_005160629
RefSeq Peptide - NP_001025233
swissprot - Q5TZ29
swissprot - A0A286YAF6
ZFIN ID - ZDB-GENE-030131-9732
Ensembl - ENSDARG00000022767
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 APOBENSGALG00000016491Gallus gallus
 APOBENSG00000084674Homo sapiens
 ApobENSMUSG00000020609Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
apoba / apolipoprotein Ba / APOB* / E9Q414* / P04114* / apolipoprotein B* / Apolipoprotein B-100 Apolipoprotein B-48*ENSDARG0000004278035
apobb.2 / apolipoprotein Bb, tandem duplicate 2 / APOB* / E9Q414* / P04114* / apolipoprotein B* / Apolipoprotein B-100 Apolipoprotein B-48*ENSDARG0000007501629


Protein motifs (from Interpro)
Interpro ID Name
 IPR001747  Lipid transport protein, N-terminal
 IPR009454  Lipid transport, open beta-sheet
 IPR011030  Lipovitellin-phosvitin complex, superhelical domain
 IPR015255  Vitellinogen, open beta-sheet
 IPR015816  Vitellinogen, beta-sheet N-terminal
 IPR015817  Vitellinogen, open beta-sheet, subdomain 1
 IPR015819  Lipid transport protein, beta-sheet shell
 IPR016024  Armadillo-type fold


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006869 lipid transport IEA
 biological_processGO:0071466 cellular response to xenobiotic stimulus IDA
 molecular_functionGO:0005319 lipid transporter activity IEA


Pathways (from Reactome)
Pathway description
Scavenging by Class B Receptors
Scavenging by Class A Receptors
Scavenging by Class H Receptors
Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)
Platelet sensitization by LDL
Regulation of TLR by endogenous ligand
Cargo recognition for clathrin-mediated endocytosis
Clathrin-mediated endocytosis
VLDL assembly
Post-translational protein phosphorylation
Chylomicron assembly
Chylomicron remodeling
Chylomicron clearance
LDL clearance
LDL remodeling
Retinoid metabolism and transport


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000137 optic stalk optic stalk decreased length , abnormal
optic stalk increased thickness , abnormal
Show

 ZFA:0001094 whole organism whole organism lacks all parts of type optic chiasm , abnormal
Show

 ZFA:0009310 retinal ganglion cell retinal ganglion cell decreased amount , abnormal
Show

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSDARG00000008637 mttp / A0A0R4IVV0 / microsomal triglyceride transfer protein / P55157* / O08601* / Microsomal triglyceride transfer protein large subunit *  / reaction






 

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