ENSDARG00000022968


Danio rerio

Features
Gene ID: ENSDARG00000022968
  
Biological name :fxr1
  
Synonyms : fragile X mental retardation, autosomal homolog 1 / fxr1
  
Possible biological names infered from orthology : FMR1 autosomal homolog 1 / Fragile X mental retardation syndrome-related protein 1 / P51114 / Q61584
  
Species: Danio rerio
  
Chr. number: 22
Strand: -1
Band:
Gene start: 37542741
Gene end: 37565410
  
Corresponding Affymetrix probe sets: Dr.4820.1.S1_at (Zebrafish Array)   NM_201301_at (Zebrafish Genome Array with custom cdf files)   
  
Cross references: Ensembl peptide - ENSDARP00000095251
Ensembl peptide - ENSDARP00000124192
NCBI entrez gene - 327220     See in Manteia.
RefSeq - NM_001312881
RefSeq - NM_201301
RefSeq Peptide - NP_001299810
RefSeq Peptide - NP_958458
swissprot - F1QLR3
swissprot - F8W4G8
ZFIN ID - ZDB-GENE-030131-5431
Ensembl - ENSDARG00000022968
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 FXR1ENSGALG00000008864Gallus gallus
 FXR1ENSG00000114416Homo sapiens
 Fxr1ENSMUSG00000027680Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
fxr2 / fragile X mental retardation, autosomal homolog 2 / P51116* / FMR1 autosomal homolog 2*ENSDARG0000001626062
fmr1 / fragile X mental retardation 1 / Q06787*ENSDARG0000003743345


Protein motifs (from Interpro)
Interpro ID Name
 IPR004087  K Homology domain
 IPR004088  K Homology domain, type 1
 IPR008395  Agenet-like domain
 IPR022034  Fragile X-related 1 protein, C-terminal core
 IPR032172  Fragile X-related 1 protein, C-terminal region 1
 IPR032177  Fragile X-related 1 protein, C-terminal region 3


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001756 somitogenesis IMP
 biological_processGO:0007507 heart development IMP
 biological_processGO:0007519 skeletal muscle tissue development IMP
 biological_processGO:0017148 negative regulation of translation IBA
 biological_processGO:0048747 muscle fiber development IMP
 cellular_componentGO:0005634 nucleus IBA
 cellular_componentGO:0005737 cytoplasm IBA
 cellular_componentGO:0005844 polysome IBA
 molecular_functionGO:0003676 nucleic acid binding IEA
 molecular_functionGO:0003723 RNA binding IEA
 molecular_functionGO:0003729 mRNA binding IBA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000009 cardiac ventricle cardiac ventricle tubular , abnormal
Show

 ZFA:0000054 pericardium pericardium edematous , abnormal
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 ZFA:0000114 heart heart linear , abnormal
heart decreased functionality , abnormal
Show

 ZFA:0000155 somite somite disorganized , abnormal
somite U-shaped , abnormal
Show

 ZFA:0000471 atrium atrium tubular , abnormal
atrium elongated , abnormal
atrium separated from sinus venosus , abnormal
Show

 ZFA:0000671 horizontal myoseptum horizontal myoseptum aplastic , abnormal
Show

 ZFA:0001056 myotome myotome myofibril irregular spatial pattern , abnormal
Show

 ZFA:0001094 whole organism whole organism decreased length , abnormal
Show

 ZFA:0001117 post-vent region post-vent region decreased length , abnormal
post-vent region curvature , abnormal
post-vent region aplastic , abnormal
Show

 ZFA:0009114 muscle cell muscle cell disorganized , abnormal
Show

 ZFA:0009236 skeletal muscle myoblast skeletal muscle myoblast nucleus circular , abnormal
Show

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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