ENSDARG00000026454


Danio rerio
sistermis12proteinmismitoticchromatidcellcyclekinetochoresignalcentromeresegregationlocalizationassemblychromosomecentromericregionnuclearmindcomplexnucleusmolecularfunctionamplificationunattachedkinetochoresviamadinhibitoryseparationchromatids

Features
Gene ID: ENSDARG00000026454
  
Biological name :mis12
  
Synonyms : mis12 / MIS12 kinetochore complex component
  
Possible biological names infered from orthology : Q9CY25 / Q9H081
  
Species: Danio rerio
  
Chr. number: 5
Strand: -1
Band:
Gene start: 58990583
Gene end: 58996324
  
Corresponding Affymetrix probe sets: Dr.26453.1.S1_at (Zebrafish Array)   
  
Cross references: Ensembl peptide - ENSDARP00000032207
swissprot - F1QY72
ZFIN ID - ZDB-GENE-040426-1372
Ensembl - ENSDARG00000026454
  
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 MIS12ENSGALG00000001632Gallus gallus
 MIS12ENSG00000167842Homo sapiens
 Mis12ENSMUSG00000040599Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR008685  Centromere protein Mis12


Gene Ontology (GO)
cellular component organizationcell cyclechromosome segregationmacromolecule localizationcellular localizationcellular component biogenesiscellular component organizationcell cyclechromosome segregationmacromolecule localizationcellular localizationcellular component biogenesiscellular component organizationcell cyclechromosome segregationmacromolecule localizationcellular localizationcellular component biogenesiscellular component organizationcell cyclechromosome segregationmacromolecule localizationcellular localizationcellular component biogenesiscellular component organizationcell cyclechromosome segregationmacromolecule localizationcellular localizationcellular component biogenesiscellular component organizationcell cyclechromosome segregationmacromolecule localizationcellular localizationcellular component biogenesiscellular component organizationcell cyclechromosome segregationmacromolecule localizationcellular localizationcellular component biogenesiscellular component organizationcell cyclechromosome segregationmacromolecule localizationcellular localizationcellular component biogenesiscellular component organizationcell cyclechromosome segregationmacromolecule localizationcellular localizationcellular component biogenesiscellular component organizationcell cyclechromosome segregationmacromolecule localizationcellular localizationcellular component biogenesiscellular component orgacellular component organizationcell cyclecell cyclechromosome segregationchromosome segregationmacromolecule localizatmacromolecule localizationcellular localizationcellular localizationcellular component biogcellular component biogenesis
cellorganelleprotein-containing complexmembrane-enclosed lumencellorganelleprotein-containing complexmembrane-enclosed lumencellorganelleprotein-containing complexmembrane-enclosed lumencellorganelleprotein-containing complexmembrane-enclosed lumencellorganelleprotein-containing complexmembrane-enclosed lumencellorganelleprotein-containing complexmembrane-enclosed lumencellorganelleprotein-containing complexmembrane-enclosed lumencellorganelleprotein-containing complexmembrane-enclosed lumencellorganelleprotein-containing complexmembrane-enclosed lumencellorganelleprotein-containing complexmembrane-enclosed lumencellcellorganelleorganelleprotein-containing complexprotein-containing complexmembrane-enclosed lumenmembrane-enclosed lumen
TypeGO IDTermEv.Code
 biological_processGO:0000070 mitotic sister chromatid segregation IBA
 biological_processGO:0000278 mitotic cell cycle IEA
 biological_processGO:0007049 cell cycle IEA
 biological_processGO:0034501 protein localization to kinetochore IBA
 biological_processGO:0051382 kinetochore assembly IBA
 cellular_componentGO:0000775 chromosome, centromeric region IEA
 cellular_componentGO:0000818 nuclear MIS12/MIND complex IBA
 cellular_componentGO:0005634 nucleus IEA
 molecular_functionGO:0003674 molecular_function ND


Pathways (from Reactome)
Pathway description
Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal
Separation of Sister Chromatids
Resolution of Sister Chromatid Cohesion
RHO GTPases Activate Formins


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

0 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2025
contact: otassy@igbmc.fr