ENSDARG00000027529


Danio rerio

Features
Gene ID: ENSDARG00000027529
  
Biological name :hmox1a
  
Synonyms : heme oxygenase 1a / hmox1a
  
Possible biological names infered from orthology : heme oxygenase 1 / HMOX1 / P09601 / P14901
  
Species: Danio rerio
  
Chr. number: 3
Strand: -1
Band:
Gene start: 26011482
Gene end: 26017831
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSDARP00000144932
Ensembl peptide - ENSDARP00000038993
NCBI entrez gene - 791518     See in Manteia.
RefSeq - NM_001127516
RefSeq Peptide - NP_001120988
swissprot - B0UXS0
ZFIN ID - ZDB-GENE-030131-3102
Ensembl - ENSDARG00000027529
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 HMOX1ENSGALG00000012550Gallus gallus
 HMOX1ENSG00000100292Homo sapiens
 Hmox1ENSMUSG00000005413Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
hmox2b / heme oxygenase 2b / HMOX2* / O70252* / P30519* / heme oxygenase 2* / Mus musculus heme oxygenase 2 (Hmox2), transcript variant 3, mRNA.*ENSDARG0000007845241
hmox2a / heme oxygenase 2a / HMOX2* / O70252* / P30519* / heme oxygenase 2* / Mus musculus heme oxygenase 2 (Hmox2), transcript variant 3, mRNA.*ENSDARG0000011469539


Protein motifs (from Interpro)
Interpro ID Name
 IPR002051  Haem oxygenase
 IPR016053  Haem oxygenase-like
 IPR016084  Haem oxygenase-like, multi-helical
 IPR018207  Haem oxygenase conserved site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001666 response to hypoxia IDA
 biological_processGO:0006788 heme oxidation IBA
 biological_processGO:0006979 response to oxidative stress IBA
 biological_processGO:0042167 heme catabolic process IBA
 biological_processGO:0043576 regulation of respiratory gaseous exchange IMP
 biological_processGO:0055072 iron ion homeostasis IBA
 biological_processGO:0055114 oxidation-reduction process IEA
 biological_processGO:0071466 cellular response to xenobiotic stimulus IDA
 cellular_componentGO:0016020 membrane IBA
 molecular_functionGO:0004392 heme oxygenase (decyclizing) activity IMP
 molecular_functionGO:0020037 heme binding IBA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
Heme degradation
Iron uptake and transport


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000009 cardiac ventricle cardiac ventricle increased volume , abnormal
Show

 ZFA:0000037 anatomical structure anatomical structure decreased amount , abnormal
Show

 ZFA:0000114 heart heart absent , abnormal
Show

 ZFA:0001094 whole organism whole organism decreased amount , abnormal
whole organism heme oxygenase (decyclizing) activity decreased process quality , abnormal
Show

 ZFA:0009306 neuroepithelial cell neuroepithelial cell decreased amount , abnormal
Show

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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