ENSGALG00000012550


Gallus gallus

Features
Gene ID: ENSGALG00000012550
  
Biological name :HMOX1
  
Synonyms : heme oxygenase 1 / HMOX1
  
Possible biological names infered from orthology : P09601 / P14901
  
Species: Gallus gallus
  
Chr. number: 1
Strand: -1
Band:
Gene start: 52153748
Gene end: 52159902
  
Corresponding Affymetrix probe sets: Gga.2039.1.S1_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000036970
NCBI entrez gene - 396287     See in Manteia.
RefSeq - NM_205344
RefSeq Peptide - NP_990675
swissprot - F1NQF4
Ensembl - ENSGALG00000012550
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 hmox1aENSDARG00000027529Danio rerio
 HMOX1ENSG00000100292Homo sapiens
 Hmox1ENSMUSG00000005413Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
HMOX2 / heme oxygenase 2 / O70252* / P30519* / Mus musculus heme oxygenase 2 (Hmox2), transcript variant 3, mRNA.*ENSGALG0000000763849


Protein motifs (from Interpro)
Interpro ID Name
 IPR002051  Haem oxygenase
 IPR016053  Haem oxygenase-like
 IPR016084  Haem oxygenase-like, multi-helical
 IPR018207  Haem oxygenase conserved site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0002246 wound healing involved in inflammatory response IEA
 biological_processGO:0006788 heme oxidation IEA
 biological_processGO:0006879 cellular iron ion homeostasis IEA
 biological_processGO:0006979 response to oxidative stress IEA
 biological_processGO:0016239 positive regulation of macroautophagy IEA
 biological_processGO:0016242 negative regulation of macroautophagy IEA
 biological_processGO:0034101 erythrocyte homeostasis IEA
 biological_processGO:0034395 regulation of transcription from RNA polymerase II promoter in response to iron IEA
 biological_processGO:0034605 cellular response to heat IEA
 biological_processGO:0035094 response to nicotine IEA
 biological_processGO:0042167 heme catabolic process IEA
 biological_processGO:0042168 heme metabolic process IEA
 biological_processGO:0043065 positive regulation of apoptotic process IEA
 biological_processGO:0045766 positive regulation of angiogenesis IEA
 biological_processGO:0048661 positive regulation of smooth muscle cell proliferation IEA
 biological_processGO:0048662 negative regulation of smooth muscle cell proliferation IEA
 biological_processGO:0051260 protein homooligomerization IEA
 biological_processGO:0055072 iron ion homeostasis IEA
 biological_processGO:0055114 oxidation-reduction process IEA
 biological_processGO:0071243 cellular response to arsenic-containing substance IEA
 biological_processGO:0071276 cellular response to cadmium ion IEA
 biological_processGO:0071456 cellular response to hypoxia IEA
 biological_processGO:0072719 cellular response to cisplatin IEA
 biological_processGO:0090050 positive regulation of cell migration involved in sprouting angiogenesis IEA
 biological_processGO:1902042 negative regulation of extrinsic apoptotic signaling pathway via death domain receptors IEA
 biological_processGO:1903589 positive regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis IEA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005783 endoplasmic reticulum IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0048471 perinuclear region of cytoplasm IEA
 molecular_functionGO:0004392 heme oxygenase (decyclizing) activity IEA
 molecular_functionGO:0020037 heme binding IEA
 molecular_functionGO:0042803 protein homodimerization activity IEA


Pathways (from Reactome)
Pathway description
Heme degradation
Iron uptake and transport


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

0 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2025
contact: otassy@igbmc.fr