ENSDARG00000028396


Danio rerio

Features
Gene ID: ENSDARG00000028396
  
Biological name :fkbp5
  
Synonyms : FK506 binding protein 5 / fkbp5
  
Possible biological names infered from orthology : Peptidyl-prolyl cis-trans isomerase FKBP5 / Q13451 / Q64378
  
Species: Danio rerio
  
Chr. number: 6
Strand: 1
Band:
Gene start: 41096058
Gene end: 41117242
  
Corresponding Affymetrix probe sets: Dr.2675.1.A1_at (Zebrafish Array)   NM_213149_at (Zebrafish Genome Array with custom cdf files)   
  
Cross references: Ensembl peptide - ENSDARP00000038578
Ensembl peptide - ENSDARP00000154791
NCBI entrez gene - 368924     See in Manteia.
RefSeq - XM_005166021
RefSeq - NM_213149
RefSeq Peptide - NP_998314
swissprot - Q801U5
ZFIN ID - ZDB-GENE-030616-630
Ensembl - ENSDARG00000028396
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 FKBP5ENSGALG00000042148Gallus gallus
 FKBP5ENSG00000096060Homo sapiens
 Fkbp5ENSMUSG00000024222Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
fkbp4 / FK506 binding protein 4 / P30416* / Q02790* / Peptidyl-prolyl cis-trans isomerase FKBP4 Peptidyl-prolyl cis-trans isomerase FKBP4, N-terminally processed*ENSDARG0000000844751
fkbp1aa / FK506 binding protein 1AaENSDARG0000002268410
fkbp1ab / FK506 binding protein 1AbENSDARG0000003356710
fkbp1b / FK506 binding protein 1bENSDARG0000005262510
fkbp3 / FK506 binding protein 3 / Q00688*ENSDARG000000980597


Protein motifs (from Interpro)
Interpro ID Name
 IPR001179  FKBP-type peptidyl-prolyl cis-trans isomerase domain
 IPR011990  Tetratricopeptide-like helical domain superfamily
 IPR013026  Tetratricopeptide repeat-containing domain
 IPR019734  Tetratricopeptide repeat
 IPR023566  Peptidyl-prolyl cis-trans isomerase, FKBP-type
 IPR031210  Peptidyl-prolyl cis-trans isomerase FKBP5


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000413 protein peptidyl-prolyl isomerization IEA
 biological_processGO:0061077 chaperone-mediated protein folding IBA
 cellular_componentGO:0005737 cytoplasm IBA
 molecular_functionGO:0003755 peptidyl-prolyl cis-trans isomerase activity IBA
 molecular_functionGO:0005528 FK506 binding IEA
 molecular_functionGO:0016853 isomerase activity IEA
 molecular_functionGO:0031072 heat shock protein binding IEA


Pathways (from Reactome)
Pathway description
HSP90 chaperone cycle for steroid hormone receptors (SHR)
ESR-mediated signaling


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSDARG00000010478 Q90474 / hsp90aa1.1 / heat shock protein 90, alpha (cytosolic), class A member 1, tandem duplicate 1 / P07900* / P07901* / HSP90AA1* / Heat shock protein HSP 90-alpha * / heat shock protein...  / complex / reaction
 ENSDARG00000008447 fkbp4 / FK506 binding protein 4 / P30416* / Q02790* / Peptidyl-prolyl cis-trans isomerase FKBP4 Peptidyl-prolyl cis-trans isomerase FKBP4, N-terminally processed*  / reaction
 ENSDARG00000037284 ptges3a / prostaglandin E synthase 3a (cytosolic) / PTGES3* / Q9R0Q7* / Q15185* / prostaglandin E synthase 3*  / complex / reaction
 ENSDARG00000004906 stip1 / stress-induced phosphoprotein 1 / P31948* / Q60864*  / complex / reaction






 

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