ENSDARG00000037284


Danio rerio

Features
Gene ID: ENSDARG00000037284
  
Biological name :ptges3a
  
Synonyms : prostaglandin E synthase 3a (cytosolic) / ptges3a
  
Possible biological names infered from orthology : prostaglandin E synthase 3 / PTGES3 / Q15185 / Q9R0Q7
  
Species: Danio rerio
  
Chr. number: 23
Strand: 1
Band:
Gene start: 27051919
Gene end: 27059998
  
Corresponding Affymetrix probe sets: Dr.5031.1.S1_at (Zebrafish Array)   NM_213170_at (Zebrafish Genome Array with custom cdf files)   
  
Cross references: Ensembl peptide - ENSDARP00000054236
NCBI entrez gene - 406449     See in Manteia.
RefSeq - NM_213170
RefSeq Peptide - NP_998335
swissprot - Q7SZQ8
ZFIN ID - ZDB-GENE-040426-2200
Ensembl - ENSDARG00000037284
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 PTGES3ENSGALG00000036837Gallus gallus
 PTGES3ENSG00000110958Homo sapiens
 Ptges3ENSMUSG00000071072Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
ptges3b / prostaglandin E synthase 3b (cytosolic) / PTGES3* / Q9R0Q7* / Q15185* / prostaglandin E synthase 3*ENSDARG0000008962677
si:ch211-131k2.3ENSDARG0000007946230
aarsd1 / alanyl-tRNA synthetase domain containing 1 / Q3THG9* / Q9BTE6*ENSDARG000000157479


Protein motifs (from Interpro)
Interpro ID Name
 IPR007052  CS domain
 IPR008978  HSP20-like chaperone


Gene Ontology (GO)
TypeGO IDTermEv.Code
No match


Pathways (from Reactome)
Pathway description
Synthesis of Prostaglandins (PG) and Thromboxanes (TX)
HSP90 chaperone cycle for steroid hormone receptors (SHR)
HSF1 activation
Attenuation phase
Aryl hydrocarbon receptor signalling
ESR-mediated signaling
Estrogen-dependent gene expression


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSDARG00000010478 Q90474 / hsp90aa1.1 / heat shock protein 90, alpha (cytosolic), class A member 1, tandem duplicate 1 / P07900* / P07901* / HSP90AA1* / Heat shock protein HSP 90-alpha * / heat shock protein...  / complex / reaction
 ENSDARG00000008447 fkbp4 / FK506 binding protein 4 / P30416* / Q02790* / Peptidyl-prolyl cis-trans isomerase FKBP4 Peptidyl-prolyl cis-trans isomerase FKBP4, N-terminally processed*  / complex / reaction
 ENSDARG00000004111 esr1 / estrogen receptor 1 / P03372* / P19785* / Estrogen receptor *  / complex
 ENSDARG00000028396 fkbp5 / FK506 binding protein 5 / Q13451* / Q64378* / Peptidyl-prolyl cis-trans isomerase FKBP5 *  / complex / reaction
 ENSDARG00000004906 stip1 / stress-induced phosphoprotein 1 / P31948* / Q60864*  / reaction
 ENSDARG00000025032 nr3c1 / nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) / P04150* / nuclear receptor subfamily 3 group C member 1*  / complex
 ENSDARG00000008818 hsf1 / heat shock transcription factor 1 / P38532* / Q00613* / heat shock factor 1*  / complex / reaction
 ENSDARG00000016454 esr2a / estrogen receptor 2a / ESR2* / O08537* / Q92731* / estrogen receptor 2* / Estrogen receptor beta *  / complex
 ENSDARG00000034181 esr2b / estrogen receptor 2b / ESR2* / O08537* / Q92731* / estrogen receptor 2* / Estrogen receptor beta *  / complex
 ENSDARG00000038835 ppid / peptidylprolyl isomerase D / Q08752* / Q9CR16* / peptidylprolyl isomerase D (cyclophilin D)*  / complex
 ENSDARG00000037284 ptges3a / prostaglandin E synthase 3a (cytosolic) / PTGES3* / Q9R0Q7* / Q15185* / prostaglandin E synthase 3*  / complex / reaction
 ENSDARG00000067976 ar / androgen receptor / P10275* / P19091*  / complex
 ENSDARG00000102082 nr3c2 / nuclear receptor subfamily 3, group C, member 2 / P08235*  / complex
 ENSDARG00000104437 aip / aryl hydrocarbon receptor interacting protein / O00170* / O08915* / AH receptor-interacting protein *  / complex






 

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