ENSDARG00000102082


Danio rerio

Features
Gene ID: ENSDARG00000102082
  
Biological name :nr3c2
  
Synonyms : nr3c2 / nuclear receptor subfamily 3, group C, member 2
  
Possible biological names infered from orthology : P08235
  
Species: Danio rerio
  
Chr. number: 1
Strand: -1
Band:
Gene start: 36935154
Gene end: 37087966
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSDARP00000130396
Ensembl peptide - ENSDARP00000136682
Ensembl peptide - ENSDARP00000130941
NCBI entrez gene - 562171     See in Manteia.
RefSeq - NM_001100403
RefSeq Peptide - NP_001093873
swissprot - A6YIH7
swissprot - A0A0R4IQ49
swissprot - A0A0R4ICJ8
ZFIN ID - ZDB-GENE-060531-23
Ensembl - ENSDARG00000102082
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 NR3C2ENSGALG00000010035Gallus gallus
 NR3C2ENSG00000151623Homo sapiens
 Nr3c2ENSMUSG00000031618Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
nr3c1 / nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) / P04150* / nuclear receptor subfamily 3 group C member 1*ENSDARG0000002503228
ar / androgen receptor / P10275* / P19091*ENSDARG0000006797623
pgr / progesterone receptor / P06401* / Q00175*ENSDARG0000003596621
esr1 / estrogen receptor 1 / P03372* / P19785* / Estrogen receptor *ENSDARG0000000411112
esr2a / estrogen receptor 2a / ESR2* / O08537* / Q92731* / estrogen receptor 2* / Estrogen receptor beta *ENSDARG0000001645412
nr4a1 / nuclear receptor subfamily 4, group A, member 1 / P12813* / P22736*ENSDARG0000000079611
esrrb / esrrga / estrogen-related receptor betaENSDARG0000000486111
esrrgb / estrogen-related receptor gamma bENSDARG0000001169611
esr2b / estrogen receptor 2b / ESR2* / O08537* / Q92731* / estrogen receptor 2* / Estrogen receptor beta *ENSDARG0000003418111
esrra / estrogen-related receptor alpha / O08580* / P11474* / Steroid hormone receptor ERR1 *ENSDARG0000006926611
nr4a2b / nuclear receptor subfamily 4, group A, member 2bENSDARG0000004453210
nr4a3 / nuclear receptor subfamily 4, group A, member 3 / Q92570* / Q9QZB6*ENSDARG0000005585410
esrrb / estrogen-related receptor beta / O95718*ENSDARG0000010084710
nr4a2a / nuclear receptor subfamily 4, group A, member 2a / NR4A2* / Q06219* / P43354* / nuclear receptor subfamily 4 group A member 2*ENSDARG000000170079
esrrd / estrogen-related receptor deltaENSDARG000000150646
FO681288.3 / ESRRG* / P62508* / P62509* / estrogen related receptor gamma* / Mus musculus estrogen-related receptor gamma (Esrrg), transcript variant 5, mRNA.*ENSDARG000001110436


Protein motifs (from Interpro)
Interpro ID Name
 IPR000536  Nuclear hormone receptor, ligand-binding domain
 IPR001628  Zinc finger, nuclear hormone receptor-type
 IPR001723  Nuclear hormone receptor
 IPR013088  Zinc finger, NHR/GATA-type


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0033555 multicellular organismal response to stress IEP
 biological_processGO:0043401 steroid hormone mediated signaling pathway IEA
 cellular_componentGO:0005634 nucleus IEA
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0003700 DNA-binding transcription factor activity IEA
 molecular_functionGO:0003707 steroid hormone receptor activity IEA
 molecular_functionGO:0008270 zinc ion binding IEA
 molecular_functionGO:0043565 sequence-specific DNA binding IEA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
HSP90 chaperone cycle for steroid hormone receptors (SHR)
Nuclear Receptor transcription pathway
SUMOylation of intracellular receptors


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000037 anatomical structure anatomical structure increased amount , abnormal
Show

 ZFA:0000368 integument integument proton export across plasma membrane increased occurrence , abnormal
Show

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSDARG00000010478 Q90474 / hsp90aa1.1 / heat shock protein 90, alpha (cytosolic), class A member 1, tandem duplicate 1 / P07900* / P07901* / HSP90AA1* / Heat shock protein HSP 90-alpha * / heat shock protein...  / complex
 ENSDARG00000008447 fkbp4 / FK506 binding protein 4 / P30416* / Q02790* / Peptidyl-prolyl cis-trans isomerase FKBP4 Peptidyl-prolyl cis-trans isomerase FKBP4, N-terminally processed*  / complex
 ENSDARG00000037284 ptges3a / prostaglandin E synthase 3a (cytosolic) / PTGES3* / Q9R0Q7* / Q15185* / prostaglandin E synthase 3*  / complex
 ENSDARG00000007438 ube2ib / Q9W6H5 / ubiquitin-conjugating enzyme E2Ib / UBE2I* / P63279* / ubiquitin conjugating enzyme E2 I*  / reaction
 ENSDARG00000044267 sumo1 / Q7SZR5 / small ubiquitin-like modifier 1 / P63166* / P63165* / Small ubiquitin-related modifier 1 *  / complex / reaction
 ENSDARG00000052649 Q9DDJ0 / ube2ia / ubiquitin-conjugating enzyme E2Ia / UBE2I* / P63280* / P63279* / ubiquitin conjugating enzyme E2 I*  / reaction






 

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