ENSDARG00000044532


Danio rerio

Features
Gene ID: ENSDARG00000044532
  
Biological name :nr4a2b
  
Synonyms : nr4a2b / nuclear receptor subfamily 4, group A, member 2b
  
Possible biological names infered from orthology :
  
Species: Danio rerio
  
Chr. number: 6
Strand: 1
Band:
Gene start: 12462079
Gene end: 12466550
  
Corresponding Affymetrix probe sets: Dr.12803.1.A1_at (Zebrafish Array)   
  
Cross references: Ensembl peptide - ENSDARP00000065384
Ensembl peptide - ENSDARP00000154564
swissprot - F1QK43
ZFIN ID - ZDB-GENE-040718-103
Ensembl - ENSDARG00000044532
  
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
No match


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
nr4a2a / nuclear receptor subfamily 4, group A, member 2a / NR4A2* / Q06219* / P43354* / nuclear receptor subfamily 4 group A member 2*ENSDARG0000001700775
nr4a3 / nuclear receptor subfamily 4, group A, member 3 / Q92570* / Q9QZB6*ENSDARG0000005585449
nr4a1 / nuclear receptor subfamily 4, group A, member 1 / P12813* / P22736*ENSDARG0000000079648
esrrb / esrrga / estrogen-related receptor betaENSDARG0000000486120
esrrgb / estrogen-related receptor gamma bENSDARG0000001169618
esr2b / estrogen receptor 2b / ESR2* / O08537* / Q92731* / estrogen receptor 2* / Estrogen receptor beta *ENSDARG0000003418118
esrra / estrogen-related receptor alpha / O08580* / P11474* / Steroid hormone receptor ERR1 *ENSDARG0000006926618
esrrb / estrogen-related receptor beta / O95718*ENSDARG0000010084718
esr1 / estrogen receptor 1 / P03372* / P19785* / Estrogen receptor *ENSDARG0000000411117
esr2a / estrogen receptor 2a / ESR2* / O08537* / Q92731* / estrogen receptor 2* / Estrogen receptor beta *ENSDARG0000001645417
nr3c1 / nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) / P04150* / nuclear receptor subfamily 3 group C member 1*ENSDARG0000002503217
ar / androgen receptor / P10275* / P19091*ENSDARG0000006797616
nr3c2 / nuclear receptor subfamily 3, group C, member 2 / P08235*ENSDARG0000010208216
pgr / progesterone receptor / P06401* / Q00175*ENSDARG0000003596614
esrrd / estrogen-related receptor deltaENSDARG0000001506410
FO681288.3 / ESRRG* / P62508* / P62509* / estrogen related receptor gamma* / Mus musculus estrogen-related receptor gamma (Esrrg), transcript variant 5, mRNA.*ENSDARG0000011104310


Protein motifs (from Interpro)
Interpro ID Name
 IPR000536  Nuclear hormone receptor, ligand-binding domain
 IPR001628  Zinc finger, nuclear hormone receptor-type
 IPR001723  Nuclear hormone receptor
 IPR003070  Orphan nuclear receptor
 IPR003073  Orphan nuclear receptor, NURR type
 IPR013088  Zinc finger, NHR/GATA-type


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0021884 forebrain neuron development IMP
 biological_processGO:0021953 central nervous system neuron differentiation IMP
 biological_processGO:0030522 intracellular receptor signaling pathway IEA
 biological_processGO:0043401 steroid hormone mediated signaling pathway IEA
 biological_processGO:0071542 dopaminergic neuron differentiation IGI
 cellular_componentGO:0005634 nucleus IEA
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0003700 DNA-binding transcription factor activity IEA
 molecular_functionGO:0003707 steroid hormone receptor activity IEA
 molecular_functionGO:0004879 nuclear receptor activity IEA
 molecular_functionGO:0008270 zinc ion binding IEA
 molecular_functionGO:0043565 sequence-specific DNA binding IEA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000008 brain brain neuron apoptotic , abnormal
Show

 ZFA:0000402 olfactory bulb olfactory bulb adrenergic neuron decreased amount , abnormal
Show

 ZFA:0000418 pretectum pretectum adrenergic neuron decreased amount , abnormal
Show

 ZFA:0000470 preoptic area preoptic area adrenergic neuron decreased amount , abnormal
Show

 ZFA:0000633 caudal tuberculum caudal tuberculum adrenergic neuron decreased amount , abnormal
Show

 ZFA:0001094 whole organism whole organism increased behavioural activity , abnormal
Show

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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