ENSDARG00000069266


Danio rerio

Features
Gene ID: ENSDARG00000069266
  
Biological name :esrra
  
Synonyms : esrra / estrogen-related receptor alpha
  
Possible biological names infered from orthology : O08580 / P11474 / Steroid hormone receptor ERR1
  
Species: Danio rerio
  
Chr. number: 21
Strand: 1
Band:
Gene start: 26606741
Gene end: 26634099
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSDARP00000023136
Ensembl peptide - ENSDARP00000144183
Ensembl peptide - ENSDARP00000120639
NCBI entrez gene - 405891     See in Manteia.
RefSeq - NM_212955
RefSeq Peptide - NP_998120
swissprot - A0A286YAH6
swissprot - F1QQS8
swissprot - E9QJE1
swissprot - Q6Q6F6
ZFIN ID - ZDB-GENE-990415-68
Ensembl - ENSDARG00000069266
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ESRRAENSG00000173153Homo sapiens
 EsrraENSMUSG00000024955Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
esrrb / estrogen-related receptor beta / O95718*ENSDARG0000010084761
esrrb / esrrga / estrogen-related receptor betaENSDARG0000000486160
esrrgb / estrogen-related receptor gamma bENSDARG0000001169659
esr1 / estrogen receptor 1 / P03372* / P19785* / Estrogen receptor *ENSDARG0000000411134
esr2a / estrogen receptor 2a / ESR2* / O08537* / Q92731* / estrogen receptor 2* / Estrogen receptor beta *ENSDARG0000001645434
esr2b / estrogen receptor 2b / ESR2* / O08537* / Q92731* / estrogen receptor 2* / Estrogen receptor beta *ENSDARG0000003418133
FO681288.3 / ESRRG* / P62508* / P62509* / estrogen related receptor gamma* / Mus musculus estrogen-related receptor gamma (Esrrg), transcript variant 5, mRNA.*ENSDARG0000011104330
nr4a1 / nuclear receptor subfamily 4, group A, member 1 / P12813* / P22736*ENSDARG0000000079625
nr3c1 / nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) / P04150* / nuclear receptor subfamily 3 group C member 1*ENSDARG0000002503225
nr4a3 / nuclear receptor subfamily 4, group A, member 3 / Q92570* / Q9QZB6*ENSDARG0000005585425
ar / androgen receptor / P10275* / P19091*ENSDARG0000006797625
nr3c2 / nuclear receptor subfamily 3, group C, member 2 / P08235*ENSDARG0000010208225
nr4a2a / nuclear receptor subfamily 4, group A, member 2a / NR4A2* / Q06219* / P43354* / nuclear receptor subfamily 4 group A member 2*ENSDARG0000001700724
nr4a2b / nuclear receptor subfamily 4, group A, member 2bENSDARG0000004453224
esrrd / estrogen-related receptor deltaENSDARG0000001506423
pgr / progesterone receptor / P06401* / Q00175*ENSDARG0000003596621


Protein motifs (from Interpro)
Interpro ID Name
 IPR000536  Nuclear hormone receptor, ligand-binding domain
 IPR001628  Zinc finger, nuclear hormone receptor-type
 IPR001723  Nuclear hormone receptor
 IPR013088  Zinc finger, NHR/GATA-type
 IPR024178  Oestrogen receptor/oestrogen-related receptor
 IPR027289  Oestrogen-related receptor


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006351 transcription, DNA-templated IDA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0042074 cell migration involved in gastrulation IMP
 biological_processGO:0043401 steroid hormone mediated signaling pathway IEA
 biological_processGO:0061035 regulation of cartilage development IMP
 cellular_componentGO:0005634 nucleus IC
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0003700 DNA-binding transcription factor activity IDA
 molecular_functionGO:0003707 steroid hormone receptor activity IEA
 molecular_functionGO:0005496 steroid binding IEA
 molecular_functionGO:0008270 zinc ion binding IEA
 molecular_functionGO:0043565 sequence-specific DNA binding IEA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
Nuclear Receptor transcription pathway


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0001056 myotome myotome increased amount , abnormal
myotome decreased amount , abnormal
myotome striated muscle cell differentiation decreased occurrence , abnormal
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 ZFA:0001114 head head apoptotic process increased occurrence , abnormal
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 ZFA:0001115 trunk trunk apoptotic process increased occurrence , abnormal
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 ZFA:0001307 pharyngeal musculature pharyngeal musculature increased amount , abnormal
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 ZFA:0001400 ceratohyal cartilage ceratohyal cartilage malformed , abnormal
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 ZFA:0001460 pharyngeal arch cartilage pharyngeal arch cartilage embryonic viscerocranium morphogenesis decreased process quality , abnormal
pharyngeal arch cartilage increased amount , abnormal
pharyngeal arch cartilage cartilage development decreased process quality , abnormal
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 ZFA:0001461 chondrocranium cartilage chondrocranium cartilage decreased size , abnormal
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 ZFA:0001516 ceratobranchial cartilage ceratobranchial cartilage malformed , abnormal
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 ZFA:0001613 pharyngeal arch 3-7 pharyngeal arch 3-7 decreased amount , abnormal
pharyngeal arch 3-7 cartilage development decreased process quality , abnormal
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Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSDARG00000067829 ppargc1a / peroxisome proliferator-activated receptor gamma, coactivator 1 alpha / Q9UBK2* / PPARG coactivator 1 alpha*  / complex






 

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