ENSDARG00000011696


Danio rerio
receptoresrrgbhormonebindingnuclearzinctranscriptionsteroidfingeroestrogen-relateddna-templatedotolithoticvesiclednaactivityionligand-bindingdomainreceptor-typenhrgata-typeoestrogenregulationformationmediatedsignalingpathwaydevelopmentnucleusdna-binding

Features
Gene ID: ENSDARG00000011696
  
Biological name :esrrgb
  
Synonyms : esrrgb / estrogen-related receptor gamma b
  
Possible biological names infered from orthology :
  
Species: Danio rerio
  
Chr. number: 20
Strand: -1
Band:
Gene start: 46790056
Gene end: 46817223
  
Corresponding Affymetrix probe sets: Dr.14813.1.A1_at (Zebrafish Array)   
  
Cross references: Ensembl peptide - ENSDARP00000145110
Ensembl peptide - ENSDARP00000091109
NCBI entrez gene - 407691     See in Manteia.
RefSeq - NM_001128678
RefSeq Peptide - NP_001122150
swissprot - B3DIZ0
swissprot - Q5RJ38
ZFIN ID - ZDB-GENE-040616-4
Ensembl - ENSDARG00000011696
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
No match


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
esrrb / esrrga / estrogen-related receptor betaENSDARG0000000486171
esrrb / estrogen-related receptor beta / O95718*ENSDARG0000010084764
esrra / estrogen-related receptor alpha / O08580* / P11474* / Steroid hormone receptor ERR1 *ENSDARG0000006926658
esr1 / estrogen receptor 1 / P03372* / P19785* / Estrogen receptor *ENSDARG0000000411134
esr2a / estrogen receptor 2a / ESR2* / O08537* / Q92731* / estrogen receptor 2* / Estrogen receptor beta *ENSDARG0000001645431
esr2b / estrogen receptor 2b / ESR2* / O08537* / Q92731* / estrogen receptor 2* / Estrogen receptor beta *ENSDARG0000003418131
FO681288.3 / ESRRG* / P62508* / P62509* / estrogen related receptor gamma* / Mus musculus estrogen-related receptor gamma (Esrrg), transcript variant 5, mRNA.*ENSDARG0000011104330
nr4a1 / nuclear receptor subfamily 4, group A, member 1 / P12813* / P22736*ENSDARG0000000079625
esrrd / estrogen-related receptor deltaENSDARG0000001506425
nr4a2a / nuclear receptor subfamily 4, group A, member 2a / NR4A2* / Q06219* / P43354* / nuclear receptor subfamily 4 group A member 2*ENSDARG0000001700725
nr3c2 / nuclear receptor subfamily 3, group C, member 2 / P08235*ENSDARG0000010208225
nr3c1 / nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) / P04150* / nuclear receptor subfamily 3 group C member 1*ENSDARG0000002503224
nr4a2b / nuclear receptor subfamily 4, group A, member 2bENSDARG0000004453224
nr4a3 / nuclear receptor subfamily 4, group A, member 3 / Q92570* / Q9QZB6*ENSDARG0000005585424
ar / androgen receptor / P10275* / P19091*ENSDARG0000006797622
pgr / progesterone receptor / P06401* / Q00175*ENSDARG0000003596620


Protein motifs (from Interpro)
Interpro ID Name
 IPR000536  Nuclear hormone receptor, ligand-binding domain
 IPR001628  Zinc finger, nuclear hormone receptor-type
 IPR001723  Nuclear hormone receptor
 IPR013088  Zinc finger, NHR/GATA-type
 IPR024178  Oestrogen receptor/oestrogen-related receptor
 IPR027289  Oestrogen-related receptor


Gene Ontology (GO)
nitrogen compound metabolic processbiosynthetic processcellular metabolic processprimary metabolic processorganic substance metabolic processanatomical structure developmentcell communicationresponse to endogenous stimulusresponse to chemicalcellular response to stimulusnitrogen compound metabolic processbiosynthetic processcellular metabolic processprimary metabolic processorganic substance metabolic processanatomical structure developmentcell communicationresponse to endogenous stimulusresponse to chemicalcellular response to stimulusnitrogen compound metabolic processbiosynthetic processcellular metabolic processprimary metabolic processorganic substance metabolic processanatomical structure developmentcell communicationresponse to endogenous stimulusresponse to chemicalcellular response to stimulusnitrogen compound metabolic processbiosynthetic processcellular metabolic processprimary metabolic processorganic substance metabolic processanatomical structure developmentcell communicationresponse to endogenous stimulusresponse to chemicalcellular response to stimulusnitrogen compound metabolic processbiosynthetic processcellular metabolic processprimary metabolic processorganic substance metabolic processanatomical structure developmentcell communicationresponse to endogenous stimulusresponse to chemicalcellular response to stimulusnitrogen compound metabolic processbiosynthetic processcellular metabolic processprimary metabolic processorganic substance metabolic processanatomical structure developmentcell communicationresponse to endogenous stimulusresponse to chemicalcellular response to stimulusnitrogen compound metabolic processbiosynthetic processcellular metabolic processprimary metabolic processorganic substance metabolic processanatomical structure developmentcell communicationresponse to endogenous stimulusresponse to chemicalcellular response to stimulusnitrogen compound metabolic processbiosynthetic processcellular metabolic processprimary metabolic processorganic substance metabolic processanatomical structure developmentcell communicationresponse to endogenous stimulusresponse to chemicalcellular response to stimulusnitrogen compound metabolic processbiosynthetic processcellular metabolic processprimary metabolic processorganic substance metabolic processanatomical structure developmentcell communicationresponse to endogenous stimulusresponse to chemicalcellular response to stimulusnitrogen compound metabolic processbiosynthetic processcellular metabolic processprimary metabolic processorganic substance metabolic processanatomical structure developmentcell communicationresponse to endogenous stimulusresponse to chemicalcellular response to stimulusnitrogen componitrogen compound metabolic processbiosynthetic pbiosynthetic processcellular metabcellular metabolic processprimary metaboprimary metabolic processorganic substaorganic substance metabolic processanatomical stranatomical structure developmentcell communicacell communicationresponse to enresponse to endogenous stimulusresponse to chresponse to chemicalcellular respocellular response to stimulus
organic cyclic compound bindingheterocyclic compound bindingDNA-binding transcription factor activitysignaling receptor activitylipid bindingion bindingorganic cyclic compound bindingheterocyclic compound bindingDNA-binding transcription factor activitysignaling receptor activitylipid bindingion bindingorganic cyclic compound bindingheterocyclic compound bindingDNA-binding transcription factor activitysignaling receptor activitylipid bindingion bindingorganic cyclic compound bindingheterocyclic compound bindingDNA-binding transcription factor activitysignaling receptor activitylipid bindingion bindingorganic cyclic compound bindingheterocyclic compound bindingDNA-binding transcription factor activitysignaling receptor activitylipid bindingion bindingorganic cyclic compound bindingheterocyclic compound bindingDNA-binding transcription factor activitysignaling receptor activitylipid bindingion bindingorganic cyclic compound bindingheterocyclic compound bindingDNA-binding transcription factor activitysignaling receptor activitylipid bindingion bindingorganic cyclic compound bindingheterocyclic compound bindingDNA-binding transcription factor activitysignaling receptor activitylipid bindingion bindingorganic cyclic compound bindingheterocyclic compound bindingDNA-binding transcription factor activitysignaling receptor activitylipid bindingion bindingorganic cyclic compound bindingheterocyclic compound bindingDNA-binding transcription factor activitysignaling receptor activitylipid bindingion bindingorganic cyclic compoundorganic cyclic compound bindingheterocyclic compound bheterocyclic compound bindingDNA-binding transcriptiDNA-binding transcription factor activitysignaling receptor actisignaling receptor activitylipid bindinglipid bindingion bindingion binding
cellorganellecellorganellecellorganellecellorganellecellorganellecellorganellecellorganellecellorganellecellorganellecellorganellecellcellorganelleorganelle
TypeGO IDTermEv.Code
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0032475 otolith formation IMP
 biological_processGO:0043401 steroid hormone mediated signaling pathway IEA
 biological_processGO:0071599 otic vesicle development IMP
 cellular_componentGO:0005634 nucleus IEA
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0003700 DNA-binding transcription factor activity IEA
 molecular_functionGO:0003707 steroid hormone receptor activity IEA
 molecular_functionGO:0005496 steroid binding IEA
 molecular_functionGO:0008270 zinc ion binding IEA
 molecular_functionGO:0043565 sequence-specific DNA binding IEA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000029 hindbrain hindbrain decreased length , abnormal
hindbrain swollen , abnormal
Show

 ZFA:0000051 otic vesicle otic vesicle circular , abnormal
Show

 ZFA:0000084 yolk yolk posterior side decreased size , abnormal
Show

 ZFA:0000107 eye eye malformed , abnormal
Show

 ZFA:0000109 forebrain forebrain shape , abnormal
Show

 ZFA:0000114 heart heart edematous , abnormal
Show

 ZFA:0000431 semicircular canal semicircular canal absent , abnormal
Show

 ZFA:0001058 caudal fin caudal fin decreased length , abnormal
Show

 ZFA:0001094 whole organism whole organism decreased length , abnormal
Show

 ZFA:0001114 head head decreased size , abnormal
Show

 ZFA:0001273 ventral mandibular arch ventral mandibular arch decreased size , abnormal
Show

 ZFA:0001617 otolith otolith absent , abnormal
Show

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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