ENSDARG00000035966


Danio rerio

Features
Gene ID: ENSDARG00000035966
  
Biological name :pgr
  
Synonyms : pgr / progesterone receptor
  
Possible biological names infered from orthology : P06401 / Q00175
  
Species: Danio rerio
  
Chr. number: 18
Strand: 1
Band:
Gene start: 41820039
Gene end: 41838419
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSDARP00000109370
swissprot - B0V3V6
ZFIN ID - ZDB-GENE-990415-214
Ensembl - ENSDARG00000035966
  
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 PGRENSGALG00000017195Gallus gallus
 PGRENSG00000082175Homo sapiens
 PgrENSMUSG00000031870Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
nr3c1 / nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) / P04150* / nuclear receptor subfamily 3 group C member 1*ENSDARG0000002503237
nr3c2 / nuclear receptor subfamily 3, group C, member 2 / P08235*ENSDARG0000010208236
ar / androgen receptor / P10275* / P19091*ENSDARG0000006797634
esr1 / estrogen receptor 1 / P03372* / P19785* / Estrogen receptor *ENSDARG0000000411120
esr2a / estrogen receptor 2a / ESR2* / O08537* / Q92731* / estrogen receptor 2* / Estrogen receptor beta *ENSDARG0000001645420
esr2b / estrogen receptor 2b / ESR2* / O08537* / Q92731* / estrogen receptor 2* / Estrogen receptor beta *ENSDARG0000003418120
esrrb / estrogen-related receptor beta / O95718*ENSDARG0000010084718
esrrb / esrrga / estrogen-related receptor betaENSDARG0000000486117
esrra / estrogen-related receptor alpha / O08580* / P11474* / Steroid hormone receptor ERR1 *ENSDARG0000006926617
esrrgb / estrogen-related receptor gamma bENSDARG0000001169616
nr4a3 / nuclear receptor subfamily 4, group A, member 3 / Q92570* / Q9QZB6*ENSDARG0000005585416
nr4a1 / nuclear receptor subfamily 4, group A, member 1 / P12813* / P22736*ENSDARG0000000079614
nr4a2a / nuclear receptor subfamily 4, group A, member 2a / NR4A2* / Q06219* / P43354* / nuclear receptor subfamily 4 group A member 2*ENSDARG0000001700714
nr4a2b / nuclear receptor subfamily 4, group A, member 2bENSDARG0000004453214
FO681288.3 / ESRRG* / P62508* / P62509* / estrogen related receptor gamma* / Mus musculus estrogen-related receptor gamma (Esrrg), transcript variant 5, mRNA.*ENSDARG0000011104310
esrrd / estrogen-related receptor deltaENSDARG000000150648


Protein motifs (from Interpro)
Interpro ID Name
 IPR000536  Nuclear hormone receptor, ligand-binding domain
 IPR001628  Zinc finger, nuclear hormone receptor-type
 IPR001723  Nuclear hormone receptor
 IPR013088  Zinc finger, NHR/GATA-type


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0030728 ovulation IMP
 biological_processGO:0042700 luteinizing hormone signaling pathway IMP
 biological_processGO:0043401 steroid hormone mediated signaling pathway IEA
 cellular_componentGO:0005634 nucleus IEA
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0003700 DNA-binding transcription factor activity IEA
 molecular_functionGO:0003707 steroid hormone receptor activity IDA
 molecular_functionGO:0005496 steroid binding IDA
 molecular_functionGO:0008270 zinc ion binding IEA
 molecular_functionGO:0043565 sequence-specific DNA binding IEA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
HSP90 chaperone cycle for steroid hormone receptors (SHR)
Nuclear Receptor transcription pathway
Estrogen-dependent gene expression


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000403 ovary ovary increased size , abnormal
Show

 ZFA:0001094 whole organism whole organism female sterile , abnormal
whole organism increased weight , abnormal
Show

 ZFA:0001115 trunk trunk increased size , abnormal
Show

 ZFA:0001569 oocyte stage V oocyte stage V immobile , abnormal
oocyte stage V non-functional , abnormal
Show

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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