ENSDARG00000028533


Danio rerio

Features
Gene ID: ENSDARG00000028533
  
Biological name :macf1a
  
Synonyms : macf1a / microtubule-actin crosslinking factor 1a
  
Possible biological names infered from orthology : MACF1 / microtubule-actin crosslinking factor 1 / Q9UPN3
  
Species: Danio rerio
  
Chr. number: 19
Strand: -1
Band:
Gene start: 35039902
Gene end: 35340027
  
Corresponding Affymetrix probe sets: Dr.1815.1.A1_at (Zebrafish Array)   
  
Cross references: Ensembl peptide - ENSDARP00000126497
Ensembl peptide - ENSDARP00000054273
Ensembl peptide - ENSDARP00000116989
Ensembl peptide - ENSDARP00000126390
swissprot - K7DYG8
swissprot - A0A0R4IDL6
swissprot - E9QFS3
swissprot - F1RA35
swissprot - K7DY63
ZFIN ID - ZDB-GENE-030131-3606
Ensembl - ENSDARG00000028533
  
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 MACF1ENSGALG00000003693Gallus gallus
 MACF1ENSG00000127603Homo sapiens
 Macf1ENSMUSG00000028649Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
DST / dystonin / Q03001*ENSDARG0000010185832
pleca / plectin a / PLEC* / Q9QXS1* / Q15149* / plectin*ENSDARG0000006259017
plecb / plectin b / PLEC* / Q9QXS1* / Q15149* / plectin*ENSDARG0000002198716
dspa / desmoplakin a / DSP* / E9Q557* / P15924* / desmoplakin*ENSDARG000000223097
si:ch211-165e15.1 / DST* / Q03001* / Q91ZU6* / dystonin*ENSDARG000001024067
evpla / envoplakin a / EVPL* / Q92817* / envoplakin*ENSDARG000000198086
wu:fi04e12 / DSP* / P15924* / desmoplakin*ENSDARG000000766736
CABZ01044281.1 / DST* / Q03001* / Q91ZU6* / dystonin*ENSDARG000001159566
eppk1 / epiplakin 1ENSDARG000000963595
CABZ01044277.1 / DST* / Q03001* / dystonin*ENSDARG000000986315
ppl / periplakin / O60437*ENSDARG000001010435


Protein motifs (from Interpro)
Interpro ID Name
 IPR001589  Actinin-type actin-binding domain, conserved site
 IPR001715  Calponin homology domain
 IPR002017  Spectrin repeat
 IPR002048  EF-hand domain
 IPR003108  GAR domain
 IPR011992  EF-hand domain pair
 IPR018159  Spectrin/alpha-actinin
 IPR018247  EF-Hand 1, calcium-binding site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0009798 axis specification IMP
 biological_processGO:0060832 oocyte animal/vegetal axis specification IMP
 molecular_functionGO:0003779 actin binding IEA
 molecular_functionGO:0005509 calcium ion binding IEA
 molecular_functionGO:0008017 microtubule binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0001175 blastodisc blastodisc absent , abnormal
Show

 ZFA:0001565 oocyte stage II oocyte stage II nucleus mislocalised , abnormal
oocyte stage II mitochondrion mislocalised , abnormal
oocyte stage II endoplasmic reticulum mislocalised , abnormal
oocyte stage II cytoplasmic part mislocalised , abnormal
oocyte stage II cortical granule mislocalised , abnormal
Show

 ZFA:0001566 oocyte stage III oocyte stage III cortical granule mislocalised , abnormal
Show

 ZFA:0001567 oocyte stage I oocyte stage I physical object quality , abnormal
oocyte stage I nucleus mislocalised , abnormal
oocyte stage I mitochondrion mislocalised , abnormal
oocyte stage I endoplasmic reticulum mislocalised , abnormal
oocyte stage I microtubule mislocalised , abnormal
oocyte stage I mitochondrial cloud increased size , abnormal
oocyte stage I mitochondrial cloud mislocalised , abnormal
Show

 ZFA:0001570 unfertilized egg unfertilized egg decreased size , abnormal
unfertilized egg malformed , abnormal
unfertilized egg cytoplasm mislocalised , abnormal
unfertilized egg chorion malformed , abnormal
Show

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

0 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2025
contact: otassy@igbmc.fr