ENSDARG00000029177


Danio rerio

Features
Gene ID: ENSDARG00000029177
  
Biological name :lnx2a
  
Synonyms : ligand of numb-protein X 2a / lnx2a
  
Possible biological names infered from orthology : ligand of numb-protein X 2 / LNX2 / Q8N448 / Q91XL2
  
Species: Danio rerio
  
Chr. number: 24
Strand: -1
Band:
Gene start: 21646317
Gene end: 21674996
  
Corresponding Affymetrix probe sets: Dr.11117.1.A1_at (Zebrafish Array)   
  
Cross references: Ensembl peptide - ENSDARP00000104570
Ensembl peptide - ENSDARP00000046210
NCBI entrez gene - 553331     See in Manteia.
RefSeq - NM_001113225
RefSeq Peptide - NP_001106696
swissprot - F1R5N4
swissprot - F1R1J1
ZFIN ID - ZDB-GENE-060228-2
Ensembl - ENSDARG00000029177
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ENSGALG00000038864Gallus gallus
 ENSGALG00000017096Gallus gallus
 LNX2ENSG00000139517Homo sapiens
 Lnx2ENSMUSG00000016520Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
lnx1 / ligand of numb-protein X 1 / O70263* / Q8TBB1*ENSDARG0000004332345
lnx2b / ligand of numb-protein X 2bENSDARG0000007147843
pdzd2 / PDZ domain containing 2 / O15018*ENSDARG0000005980118
patj / PATJ, crumbs cell polarity complex component / Q63ZW7* / Q8NI35* / Mus musculus PATJ, crumbs cell polarity complex component (Patj), transcript variant 5, mRNA.*ENSDARG0000002496416
il16 / interleukin 16 / O54824* / Q14005* / Pro-interleukin-16 Interleukin-16*ENSDARG0000010290815
pard3ab / par-3 family cell polarity regulator alpha, b / PARD3* / Q8TEW0* / Q99NH2* / par-3 family cell polarity regulator*ENSDARG0000001058312
si:dkey-92j12.5 / MPDZ* / Q8VBX6* / O75970* / multiple PDZ domain protein* / multiple PDZ domain crumbs cell polarity complex component*ENSDARG0000009467712
pard3ba / si:ch1073-345a8.1 / PARD3B* / Q8TEW8* / par-3 family cell polarity regulator beta*ENSDARG0000009267110
pard3bb / par-3 family cell polarity regulator beta b / PARD3B* / Q9CSB4* / Q8TEW8* / par-3 family cell polarity regulator beta*ENSDARG000000345558
PARD3 (1 of many) / par-3 family cell polarity regulator / PARD3* / Q8TEW0*ENSDARG000001108047
si:dkey-92i15.4ENSDARG000000783876


Protein motifs (from Interpro)
Interpro ID Name
 IPR001478  PDZ domain
 IPR001841  Zinc finger, RING-type
 IPR013083  Zinc finger, RING/FYVE/PHD-type
 IPR017907  Zinc finger, RING-type, conserved site
 IPR027370  RING-type zinc-finger, LisH dimerisation motif


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0016567 protein ubiquitination IEA
 biological_processGO:0031017 exocrine pancreas development IMP
 molecular_functionGO:0046872 metal ion binding IEA
 molecular_functionGO:0061630 ubiquitin protein ligase activity IDA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000140 pancreas pancreas increased distribution , abnormal
pancreas decreased distribution , abnormal
Show

 ZFA:0001249 exocrine pancreas exocrine pancreas decreased distribution , abnormal
exocrine pancreas decreased amount , abnormal
Show

 ZFA:0001369 anterior pancreatic bud anterior pancreatic bud decreased distribution , abnormal
anterior pancreatic bud cell proliferation decreased process quality , abnormal
Show

 ZFA:0001390 pancreatic bud pancreatic bud increased distribution , abnormal
Show

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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