ENSDARG00000029370


Danio rerio
regulationankrd6bankyringastrulationventralwntsignalingpathwaybeta-cateninrepeatrepeat-containingdomainmouthformingsecondheartdevelopmentdorsalpatternformationcellmigrationinvolvedjnkcascadedeterminationidentitycanonicalnucleuscytoplasmdestruction

Features
Gene ID: ENSDARG00000029370
  
Biological name :ankrd6b
  
Synonyms : ankrd6b / ankyrin repeat domain 6b
  
Possible biological names infered from orthology : ANKRD6 / ankyrin repeat domain 6 / Mus musculus ankyrin repeat domain 6 (Ankrd6), transcript variant 4, mRNA. / Q69ZU8 / Q9Y2G4
  
Species: Danio rerio
  
Chr. number: 20
Strand: -1
Band:
Gene start: 1203238
Gene end: 1239603
  
Corresponding Affymetrix probe sets: DrAffx.1.13.S1_at (Zebrafish Array)   NM_194423_at (Zebrafish Genome Array with custom cdf files)   
  
Cross references: Ensembl peptide - ENSDARP00000118157
Ensembl peptide - ENSDARP00000049062
NCBI entrez gene - 378477     See in Manteia.
RefSeq - NM_194423
RefSeq Peptide - NP_919404
swissprot - F6NJE0
swissprot - F1RBU2
ZFIN ID - ZDB-GENE-030916-4
Ensembl - ENSDARG00000029370
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ANKRD6ENSGALG00000015768Gallus gallus
 ANKRD6ENSG00000135299Homo sapiens
 Ankrd6ENSMUSG00000040183Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
ankrd6a / ankyrin repeat domain 6a / Q9Y2G4* / Q69ZU8* / ANKRD6* / ankyrin repeat domain 6* / Mus musculus ankyrin repeat domain 6 (Ankrd6), transcript variant 4, mRNA.*ENSDARG0000005779032
A5PMU4 / anks1b / ankyrin repeat and sterile alpha motif domain containing 1B / Q7Z6G8* / ankyrin repeat and sterile alpha motif domain-containing protein 1B isoform 6 *ENSDARG0000000351217
si:ch211-119c20.2 / Q8VHK1* / Q8WXE0* / CASKIN2* / CASK interacting protein 2*ENSDARG0000004381817
caskin1 / CASK interacting protein 1 / Q8WXD9*ENSDARG0000004610717
si:dkeyp-9d4.3 / Q6P9K8* / Q8WXD9* / CASKIN1* / CASK interacting protein 1*ENSDARG0000010016616
ankdd1a / ankyrin repeat and death domain containing 1A / Q495B1*ENSDARG0000009864713
ankdd1b / ankyrin repeat and death domain containing 1B / A6NHY2* / Q14DN9* / Ankyrin repeat and death domain-containing protein 1B *ENSDARG0000002586612
mib1 / Q804S5 / mindbomb E3 ubiquitin protein ligase 1 / Q80SY4* / Q86YT6* / E3 ubiquitin-protein ligase MIB1 *ENSDARG0000010218412
MIB2 / mindbomb E3 ubiquitin protein ligase 2 / Q96AX9*ENSDARG0000010360910
anks1ab / ankyrin repeat and sterile alpha motif domain containing 1Ab / Anks1* / Q92625* / ANKS1A* / P59672* / Ankyrin repeat and SAM domain-containing protein 1A * / ankyrin repeat and st...ENSDARG000000789015
anks1aa / ankyrin repeat and sterile alpha motif domain containing 1Aa / Anks1* / Q92625* / ANKS1A* / P59672* / Ankyrin repeat and SAM domain-containing protein 1A * / ankyrin repeat and st...ENSDARG000000623963


Protein motifs (from Interpro)
Interpro ID Name
 IPR002110  Ankyrin repeat
 IPR020683  Ankyrin repeat-containing domain


Gene Ontology (GO)
anatomical structure developmentcell communicationcellular response to stimuluslocalization of cellmovement of cell or subcellular componentnitrogen compound metabolic processresponse to stresscellular metabolic processprimary metabolic processorganic substance metabolic processanatomical structure developmentcell communicationcellular response to stimuluslocalization of cellmovement of cell or subcellular componentnitrogen compound metabolic processresponse to stresscellular metabolic processprimary metabolic processorganic substance metabolic processanatomical structure developmentcell communicationcellular response to stimuluslocalization of cellmovement of cell or subcellular componentnitrogen compound metabolic processresponse to stresscellular metabolic processprimary metabolic processorganic substance metabolic processanatomical structure developmentcell communicationcellular response to stimuluslocalization of cellmovement of cell or subcellular componentnitrogen compound metabolic processresponse to stresscellular metabolic processprimary metabolic processorganic substance metabolic processanatomical structure developmentcell communicationcellular response to stimuluslocalization of cellmovement of cell or subcellular componentnitrogen compound metabolic processresponse to stresscellular metabolic processprimary metabolic processorganic substance metabolic processanatomical structure developmentcell communicationcellular response to stimuluslocalization of cellmovement of cell or subcellular componentnitrogen compound metabolic processresponse to stresscellular metabolic processprimary metabolic processorganic substance metabolic processanatomical structure developmentcell communicationcellular response to stimuluslocalization of cellmovement of cell or subcellular componentnitrogen compound metabolic processresponse to stresscellular metabolic processprimary metabolic processorganic substance metabolic processanatomical structure developmentcell communicationcellular response to stimuluslocalization of cellmovement of cell or subcellular componentnitrogen compound metabolic processresponse to stresscellular metabolic processprimary metabolic processorganic substance metabolic processanatomical structure developmentcell communicationcellular response to stimuluslocalization of cellmovement of cell or subcellular componentnitrogen compound metabolic processresponse to stresscellular metabolic processprimary metabolic processorganic substance metabolic processanatomical structure developmentcell communicationcellular response to stimuluslocalization of cellmovement of cell or subcellular componentnitrogen compound metabolic processresponse to stresscellular metabolic processprimary metabolic processorganic substance metabolic processanatomical stranatomical structure developmentcell communicacell communicationcellular respocellular response to stimuluslocalization olocalization of cellmovement of cemovement of cell or subcellular componentnitrogen componitrogen compound metabolic processresponse to stresponse to stresscellular metabcellular metabolic processprimary metaboprimary metabolic processorganic substaorganic substance metabolic process
protein bindingprotein bindingprotein bindingprotein bindingprotein bindingprotein bindingprotein bindingprotein bindingprotein bindingprotein bindingprotein bindingprotein binding
cellorganelleprotein-containing complexcellorganelleprotein-containing complexcellorganelleprotein-containing complexcellorganelleprotein-containing complexcellorganelleprotein-containing complexcellorganelleprotein-containing complexcellorganelleprotein-containing complexcellorganelleprotein-containing complexcellorganelleprotein-containing complexcellorganelleprotein-containing complexcellcellorganelleorganelleprotein-containing complexprotein-containing complex
TypeGO IDTermEv.Code
 biological_processGO:0001702 gastrulation with mouth forming second IMP
 biological_processGO:0007507 heart development IMP
 biological_processGO:0009953 dorsal/ventral pattern formation IMP
 biological_processGO:0030178 negative regulation of Wnt signaling pathway IGI
 biological_processGO:0042074 cell migration involved in gastrulation IMP
 biological_processGO:0046330 positive regulation of JNK cascade IDA
 biological_processGO:0048264 determination of ventral identity IMP
 biological_processGO:0090090 negative regulation of canonical Wnt signaling pathway IBA
 cellular_componentGO:0005634 nucleus IBA
 cellular_componentGO:0005737 cytoplasm IBA
 cellular_componentGO:0030877 beta-catenin destruction complex NAS
 molecular_functionGO:0008013 beta-catenin binding NAS


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000155 somite somite increased width , abnormal
somite condensed , abnormal
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 ZFA:0000208 gall bladder gall bladder left side of whole organism , abnormal
gall bladder mislocalised laterally , abnormal
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 ZFA:0001094 whole organism whole organism decreased length , abnormal
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Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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