ENSDARG00000029476
Danio rerio site egf-like receptor ldlra class domain low-density lipoprotein ldl conserved endocytosis repeat calcium-binding membrane clathrin-mediated clearance vein ldlr b egf-type aspartate asparagine hydroxylation growth factor cysteine-rich superfamily six-bladed beta-propeller tolb-like receptor-mediated
Features Gene ID: ENSDARG00000029476 Biological name :ldlra Synonyms : ldlra / Possible biological names infered from orthology : LDLR / / / Species: Danio rerio Chr. number: 3 Strand: 1 Band: Gene start: 19299309 Gene end: 19323689 Corresponding Affymetrix probe sets: Cross references: Ensembl peptide - ENSDARP00000115492387529
See in Manteia .
NM_001030283 XM_005163870 NP_001025454 E9QGD4 Q7ZZT0 F6P6T4 ZDB-GENE-031217-1 ENSDARG00000029476
See expression report in BioGPS See gene description in Wikigenes See co-cited genes in PubMed Ortholog prediction (from Ensembl )Paralog prediction (from Ensembl ) ldlrb / low density lipoprotein receptor b / LDLR* / P35951* / P01130* / low density lipoprotein receptor* ENSDARG00000026759 45 lrp8 / low density lipoprotein receptor-related protein 8, apolipoprotein e receptor / Q14114* / Q924X6* / LDL receptor related protein 8* / Low-density lipoprotein receptor-related protein 8 * ENSDARG00000070074 44 vldlr / very low density lipoprotein receptor / P98155* / P98156* ENSDARG00000006257 42 lrp2b / low density lipoprotein receptor-related protein 2b ENSDARG00000007906 31 lrp1ba / low density lipoprotein receptor-related protein 1Ba / LRP1B* / Q9NZR2* / LDL receptor related protein 1B* ENSDARG00000004789 30 lrp1ab / low density lipoprotein receptor-related protein 1Ab / LRP1* / Q07954* / LDL receptor related protein 1* ENSDARG00000029146 30 lrp1aa / low density lipoprotein receptor-related protein 1Aa / LRP1* / Q07954* / LDL receptor related protein 1* ENSDARG00000097827 30 lrp2a / low density lipoprotein receptor-related protein 2a / LRP2* / P98164* / A2ARV4* / LDL receptor related protein 2* / low density lipoprotein receptor-related protein 2* ENSDARG00000102506 30 lrp1bb / low density lipoprotein receptor-related protein 1Bb / LRP1B* / Q9NZR2* / LDL receptor related protein 1B* ENSDARG00000061517 29 si:dkey-88l16.3 / Gm19410* ENSDARG00000094055 25 lrp13 / low-density lipoprotein receptor related-protein 13 / Gm19410* ENSDARG00000023479 24 lrp5 / low density lipoprotein receptor-related protein 5 / O75197* / LDL receptor related protein 5* ENSDARG00000006921 15 CABZ01071171.1 / Danio rerio low density lipoprotein receptor-related protein 4 (lrp4), mRNA. / LRP4* / Q8VI56* / O75096* / LDL receptor related protein 4* / Low-density lipoprotein recepto... ENSDARG00000116353 3 lrp6 / low density lipoprotein receptor-related protein 6 / O75581* / LDL receptor related protein 6* ENSDARG00000100143 2 lrp1ba / low density lipoprotein receptor-related protein 1Ba / Gm19410* ENSDARG00000094171 1
Protein motifs (from Interpro ) IPR000033 LDLR class B repeat IPR000152 EGF-type aspartate/asparagine hydroxylation site IPR000742 EGF-like domain IPR001881 EGF-like calcium-binding domain IPR002172 Low-density lipoprotein (LDL) receptor class A repeat IPR009030 Growth factor receptor cysteine-rich domain superfamily IPR011042 Six-bladed beta-propeller, TolB-like IPR013032 EGF-like, conserved site IPR018097 EGF-like calcium-binding, conserved site IPR023415 Low-density lipoprotein (LDL) receptor class A, conserved site
Gene Ontology (GO ) macromolecule localization establishment of localization cellular localization macromolecule localization establishment of localization cellular localization macromolecule localization establishment of localization cellular localization macromolecule localization establishment of localization cellular localization macromolecule localization establishment of localization cellular localization macromolecule localization establishment of localization cellular localization macromolecule localization establishment of localization cellular localization macromolecule localization establishment of localization cellular localization macromolecule localization establishment of localization cellular localization macromolecule localization establishment of localization cellular localization macromolecule localizationmacromolecule localization establishment of localizationestablishment of localization cellular localizationcellular localization lipoprotein particle receptor activity ion binding lipoprotein particle receptor activity ion binding lipoprotein particle receptor activity ion binding lipoprotein particle receptor activity ion binding lipoprotein particle receptor activity ion binding lipoprotein particle receptor activity ion binding lipoprotein particle receptor activity ion binding lipoprotein particle receptor activity ion binding lipoprotein particle receptor activity ion binding lipoprotein particle receptor activity ion binding lipoprotein particle receptor activitylipoprotein particle receptor activity ion bindingion binding cell membrane cell membrane cell membrane cell membrane cell membrane cell membrane cell membrane cell membrane cell membrane cell membrane cellcell membranemembrane
Pathways (from Reactome )Phenotype (from MGI , Zfin or HPO ) ZFA:0000123 liver liver increased size , abnormal
Show ZFA:0000180 caudal vein caudal vein lipid increased amount , abnormal
Show ZFA:0000477 posterior cardinal vein posterior cardinal vein has extra parts of type macrophage , abnormal
Show ZFA:0001094 whole organism whole organism increased amount , abnormal
Show ZFA:0005249 vasculature vasculature macrophage mislocalised , abnormal
Show ZFA:0005654 blood plasma blood plasma cholesterol increased amount , abnormal
Show ZFA:0009111 hepatocyte hepatocyte cellular response to lipopolysaccharide disrupted , abnormal
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Interacting proteins (from Reactome )No match
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