ENSDARG00000029911


Danio rerio

Features
Gene ID: ENSDARG00000029911
  
Biological name :casc3
  
Synonyms : cancer susceptibility candidate 3 / casc3 / Q1ECZ4
  
Possible biological names infered from orthology : cancer susceptibility 3 / O15234 / Protein CASC3 / Q8K3W3
  
Species: Danio rerio
  
Chr. number: 3
Strand: -1
Band:
Gene start: 23428953
Gene end: 23461954
  
Corresponding Affymetrix probe sets: Dr.6582.1.A1_at (Zebrafish Array)   NM_205716_at (Zebrafish Genome Array with custom cdf files)   
  
Cross references: Ensembl peptide - ENSDARP00000040064
NCBI entrez gene - 403025     See in Manteia.
RefSeq - NM_205716
RefSeq Peptide - NP_991279
swissprot - Q1ECZ4
ZFIN ID - ZDB-GENE-040308-2
Ensembl - ENSDARG00000029911
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 CASC3ENSGALG00000031813Gallus gallus
 CASC3ENSG00000108349Homo sapiens
 Casc3ENSMUSG00000078676Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR018545  Btz domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000184 nuclear-transcribed mRNA catabolic process, nonsense-mediated decay IEA
 biological_processGO:0006397 mRNA processing IEA
 biological_processGO:0006417 regulation of translation IEA
 biological_processGO:0008380 RNA splicing IEA
 biological_processGO:0051028 mRNA transport IEA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0010494 cytoplasmic stress granule IEA
 cellular_componentGO:0016607 nuclear speck IEA
 cellular_componentGO:0030425 dendrite IEA
 cellular_componentGO:0035145 exon-exon junction complex IEA
 cellular_componentGO:0036464 cytoplasmic ribonucleoprotein granule IEA
 cellular_componentGO:0042995 cell projection IEA
 cellular_componentGO:0048471 perinuclear region of cytoplasm IEA
 molecular_functionGO:0003723 RNA binding IEA


Pathways (from Reactome)
Pathway description
Transport of Mature mRNA derived from an Intron-Containing Transcript
mRNA Splicing - Major Pathway
mRNA 3-end processing
Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSDARG00000016516 rbm8a / Q5D018 / RNA binding motif protein 8A / Q9CWZ3* / Q9Y5S9* / Rbm8a2* / RNA-binding protein 8A *  / complex
 ENSDARG00000038635 magoh / Q566Y8 / mago homolog, exon junction complex core component / Q96A72* / MAGOHB* / P61326* / P61327* / Protein mago nashi homolog * / mago homolog B, exon junction complex core component*  / complex
 ENSDARG00000069297 upf3a / B0S733 / UPF3A, regulator of nonsense mediated mRNA decay / Q9H1J1* / UPF3 regulator of nonsense transcripts homolog A (yeast)*  / complex






 

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