ENSDARG00000069297


Danio rerio

Features
Gene ID: ENSDARG00000069297
  
Biological name :upf3a
  
Synonyms : B0S733 / upf3a / UPF3A, regulator of nonsense mediated mRNA decay
  
Possible biological names infered from orthology : Q9H1J1 / UPF3 regulator of nonsense transcripts homolog A (yeast)
  
Species: Danio rerio
  
Chr. number: 9
Strand: -1
Band:
Gene start: 34902971
Gene end: 34915394
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSDARP00000091501
Ensembl peptide - ENSDARP00000114416
NCBI entrez gene - 566608     See in Manteia.
RefSeq - NM_001202448
RefSeq Peptide - NP_001189377
swissprot - B0S733
swissprot - A0A0H2UKF3
ZFIN ID - ZDB-GENE-060721-2
Ensembl - ENSDARG00000069297
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 UPF3AENSGALG00000016815Gallus gallus
 UPF3AENSG00000169062Homo sapiens
 Upf3aENSMUSG00000038398Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
upf3b / UPF3B, regulator of nonsense mediated mRNA decay / Q9BZI7* / UPF3 regulator of nonsense transcripts homolog B (yeast)*ENSDARG0000000048944


Protein motifs (from Interpro)
Interpro ID Name
 IPR000504  RNA recognition motif domain
 IPR005120  UPF3 domain
 IPR034978  Regulator of nonsense transcripts 3A


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000184 nuclear-transcribed mRNA catabolic process, nonsense-mediated decay IEA
 biological_processGO:0006913 nucleocytoplasmic transport IEA
 biological_processGO:0051028 mRNA transport IEA
 cellular_componentGO:0005622 intracellular IEA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005737 cytoplasm IEA
 molecular_functionGO:0003676 nucleic acid binding IEA
 molecular_functionGO:0003723 RNA binding IEA


Pathways (from Reactome)
Pathway description
Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000012 central nervous system central nervous system necrotic , abnormal
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 ZFA:0000029 hindbrain hindbrain elongated , abnormal
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 ZFA:0000042 midbrain hindbrain boundary midbrain hindbrain boundary decreased size , abnormal
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Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSDARG00000016516 rbm8a / Q5D018 / RNA binding motif protein 8A / Q9CWZ3* / Q9Y5S9* / Rbm8a2* / RNA-binding protein 8A *  / complex
 ENSDARG00000029911 casc3 / Q1ECZ4 / cancer susceptibility candidate 3 / Q8K3W3* / O15234* / Protein CASC3 * / cancer susceptibility 3*  / complex
 ENSDARG00000038635 magoh / Q566Y8 / mago homolog, exon junction complex core component / Q96A72* / MAGOHB* / P61326* / P61327* / Protein mago nashi homolog * / mago homolog B, exon junction complex core component*  / complex






 

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